ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini +7 more
wiley +1 more source
Growth, History, or Institutions? What Explains State Fragility in Sub-Saharan Africa [PDF]
We explore the determinants of state fragility in sub-Saharan Africa. Controlling for a wide range of economic, demographic, geographic and istitutional regressors, we find that institutions, and in particular the civil liberties index and the number of ...
Andrea Guerzoni, Graziella Bertocchi
core +3 more sources
The South African Journal of Science: A biography
This article provides a chronological account of the South African Journal of Science (SAJS) from its inception in 1903 up to the present. This approach clarifies the shifts in emphasis and purpose as the Journal moved through changing publishing ...
Jane Carruthers
doaj +1 more source
The Genetic Structure and History of Africans and African Americans. [PDF]
Africa is the source of all modern humans, but characterization of genetic variation and of relationships among populations across the continent has been enigmatic. We studied 121 African populations, four African American populations, and 60 non-African
A. A. Awomoyi +61 more
core +1 more source
Amyotrophic Lateral Sclerosis Prevalence Projection in 2040: A Less Rare Disease
ABSTRACT Objective To project ALS prevalence across multiple countries through 2040, accounting for both population aging and increased survival. Methods Data from the Piemonte and Valle d'Aosta ALS register (PARALS) was used to estimate the trends in incidence and prevalence from 2005 to 2019. Survival trends over this period were also assessed.
Rosario Vasta +18 more
wiley +1 more source
Diffusion Approximations for Demographic Inference: DaDi [PDF]
Models of demographic history (population sizes, migration rates, and divergence times) inferred from genetic data complement archeology and serve as null models in genome scans for selection. Most current inference methods are computationally limited to
Carlos D. Bustamante +3 more
core +1 more source
Portable Low‐Field Magnetic Resonance Imaging in People With Human Immunodeficiency Virus
ABSTRACT Objective The aging population of people with HIV (PWH) raises heightened concerns regarding accelerated aging and dementia. Portable, low‐field MRI (LF‐MRI) is an innovative technology that could enhance access and facilitate routine monitoring of PWH.
Annabel Sorby‐Adams +14 more
wiley +1 more source
Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin +2 more
wiley +1 more source
From advocating to attending: The shifting role of the South African Council of Churches during the COVID-19 pandemic [PDF]
The South African Council of Churches (SACC) has been on the receiving end of criticism from scholars since 1994. This article contends that the 2020 national lockdown at the height of the COVID-19 pandemic was the pinnacle of the renewal of the SACC ...
Dr Thembelani Jentile
doaj +1 more source
Land Reform for a Landless Chief in South Africa: History and Land Restitution in KwaZulu-Natal [PDF]
Jill E. Kelly
openalex +1 more source

