Results 31 to 40 of about 121,400 (290)
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Techno-Religion and Cyberspace Spirituality in Dystopian Video Games
Religions, 2023 Once a niche part of the cyber community, video games today represent one of the major industries and “the combination of technology and spiritualist narratives”.
Tijana Rupcic
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Microclimate of the Natural History Museum, Vienna
HeritageClimate change increases the importance of maintaining environmental conditions suitable for preventive conservation within museums. The microclimates at the Natural History Museum of Vienna, a large national collection housed within a classical building,
Peter Brimblecombe +4 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Jubiläumsbilder. Drei Ausstellungen zum Staatsvertragsgedenken 2005
Österreichische Zeitschrift für Geschichtswissenschaften, 2006 On the occasion of the 50th anniversary of the Austrian State Treaty (May 15, 1955) many commemorative events including a series of exhibitions took place in Austria.
Ulrike Felber
doaj +1 more source
The status of computing and history teaching in Austria
Historical Social Research, 1988 Historical Social Research, 15(1), 79 ...
Eder, Franz, Fuchs, Eduard
openaire +4 more sources
Geology and sedimentary history of Lake Traunsee (Salzkammergut, Austria) [PDF]
Hydrobiologia, 1986 Traunsee was formed by glacial overdeepening of a pre-existing fault system. Present-day morphology is characterized by a deep (189 m) narrow trough with steep slopes (> 50°) in the southern part surrounded by the Northern Calcareous Alps. The northern part of the lake is bordered by flysch and glacial deposits with gentle slopes (< 30°) and exhibits ...
Schneider, Jürgen +2 more
openaire +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source