Results 81 to 90 of about 189,918 (307)

Carl Schorlemmer (1834-1892) – The Red Chemist

open access: yesSubstantia
This article presents the life and work of Carl Schorlemmer, one of the least remembered chemists in Organic Chemistry from the second half of the 19th century.
Juergen Heinrich Maar
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

La voluptuosidad en los alambiques

open access: yesIbérica, 2003
Chemistry as a science was born in the second half of the 18th century, although some philosophers express their reservations about it by fixing the debate on apodictic certainty terms and rejecting, as insufficient, the empirical certainty that does not
María José Gómez Perales
doaj  

ENTRE TIPOS E RADICAIS: A CONSTRUÇÃO DO CONCEITO DE VALÊNCIA

open access: yesQuímica Nova
This paper presents a historical case study regarding the development of the concept of valence in late nineteenth and early twentieth centuries. The case study focuses on Edward Frankland’s contribution to the process which lead to the convergence of ...
Helena S. Alvares Nogueira   +1 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Oleksandr Ishchenko: And Gladly Would He Learn, and Gladly Teach

open access: yesЖурнал органічної та фармацевтичної хімії
The Ukrainian school of organic dye chemistry has long received worldwide recognition. Among the scientists whose achievements embody this success is Academician Oleksandr Oleksandrovych Ishchenko.
Andrii V. Kulinich
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

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