Results 31 to 40 of about 542,342 (268)

Genomic insights into the complex demographic history and inbreeding phenomena during Zhou Dynasty on the Central Plains of China

Frontiers in Microbiology
In the Central Plains of China during the Zhou Dynasty (1046-256 BCE), the social hierarchy gradually solidified, accompanied by frequent wars and the phenomena of multicultural and multi-ethnic integration. These social phenomena collectively influenced
Xiyan Wu, Xiyan Wu, Baoxu Ding, Linyi Nie, Canshuo Zhong, Pengxiang Liu, Jingteng Liang, Lin Wang, Xiangping Gao, Jiyin Wei, Yawei Zhou   +10 more
doaj   +1 more source

The analysis and identification of charred suspected tea remains unearthed from Warring State Period Tomb

Scientific Reports, 2021
Recently, a bowl containing charred suspected tea remains unearthed from the early stage of Warring States period tomb in Zoucheng City, Shandong Province, China. To identify the remains is significant for understanding the origin of tea and tea drinking
Jianrong Jiang, Guoquan Lu, Qing Wang, Shuya Wei   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Faunal remains data from Paleolithic-early Iron Age archaeological sites in the Qinghai-Tibet Plateau in China

Scientific Data
According to published archaeological sources, zooarchaeological data collection on the Qinghai-Tibet Plateau and its marginal and transitional areas is inadequate, and relevant datasets have not been published. For this reason, we collected and collated
Kaidi Ren, Lele Ren
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

History, Culture and Politics of the Kurds: A Short Overview

Kulturní Studia, 2023
This article provides a comprehensive overview of the Kurds, the world’s largest people without a state of their own, and explores their complex and often tragic history.
Michiel Leezenberg
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Seasonal Characteristics and Source Contributions Analysis of PM2.5 in Mountainous Cities

Aerosol and Air Quality Research
PM2.5 is an important component of haze, and an in-depth understanding of PM2.5 pollution characteristics and potential source areas is of great significance for the accurate prevention and control of PM2.5 pollution. Previous studies have mostly focused
Qian Wang, Xiao-yue Mei, Di-chen Zhao, Qi-peng Zhang   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source