Results 61 to 70 of about 542,342 (268)

Burials of the Late Antiquity from the Burial Mound Mandesarka-6

Нижневолжский археологический вестник, 2018
The paper is devoted to the publication of archaeological research of the burial mound Mandesarka-6, located at the top of the watershed of the rivers Mandesarka and Kayrahta in the southern Urals. The burial mound includes 11 groundwater mounds: 9 round,
Mariya R. Makurova, Yuriy S. Makurov, Ilya E. Lyubchanskiy, Evgeniy O. Shimanskiy   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

A Multi-Scenario Simulation and Driving Factor Analysis of Production–Living–Ecological Land in China’s Main Grain Producing Areas: A Case Study of the Huaihe River Eco-Economic Belt

Agriculture
The Huaihe River Eco-Economic Belt (HREEB) is a pivotal region in China’s national strategic planning. Land use in this region is crucial to improving ecological quality and ensuring food security.
Wenfeng Hu, Junhao Cheng, Mengtian Zheng, Xiaolong Jin, Junqiang Yao, Fei Guo   +5 more
doaj   +1 more source

वैदिक कालीन आयुध निर्माण तकनीकी

Dev Sanskriti: Interdisciplinary International Journal, 2015
भारतीय संस्कृति एक हाथ में शस्त्र तथा दूसरे हाथ में शास्त्र का संदेश देती है। वैदिक काल मे तत्कालीन ऋषि मुनियों ने दुष्टों के दमन हेतु आयुध निर्माण पद्धति को विकसित किया था। मध्यकाल और आधुनिक काल में भारत में रही विदेशी ताक़तों ने आयुध निर्माण के क्षेत ...
Manoj Kumar Rao, Ipshit Pratap Singh
doaj   +1 more source

Research on the Communication Strategy of History and Culture in Shaanxi Based on BP Neural Network Model. [PDF]

Comput Intell Neurosci, 2022
Xie D, Yin C.
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

The River God Cult and the Reshaping of Political Authority—Reading Inscriptions from the Hezhong Area in Tang China

Religions
The River God cult held a significant place in state rituals in imperial China. While scholars have primarily focused on the evolution of the River God sacrificial system, with its interplay of the official granting of noble titles and popular beliefs ...
Aihua Jiang, Longxiang Ma
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source