Results 151 to 160 of about 6,995,982 (396)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

UNH Faculty Abroad Series, Fall 2011 [PDF]

open access: yes, 2011
Eun Kyeong Cho UNH Department of Education September 27, 2011 Early Childhood Education and Cross-Cultural Collaboration: Lessons from South Korea Alynna Lyon UNH Department of Political Science October 18, 2011 Strategic Humanitarian Intervention ...
Center for International Education
core   +2 more sources

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Conceptual history and History of Education

open access: yesHistoria de la Educación, 2013
After noting the importance of linguistic turn in the field of historiography, the two leading currents in the field of conceptual history are identi- fied, the Cambridge school and Reinhart Koselleck’s Begriffsgeschichte.
Conrad VILANOU I TORRANO
doaj  

Federal Aid to Schools: Its Limited Future [PDF]

open access: yes, 1974
A brief history of the development of the limited-purpose Federal education programs is used as background to make a case for the diminishing likelihood of a major Federal initiative Beyond the presently enacted categorical grant programs.
Timpane, P. Michael
core   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Ambonsche Studiefonds and Sarekat Ambon as Forums for Moluccan Nationalists to Initiate Indonesian Independence Movement

open access: yesIHiS (Indonesian Historical Studies)
This research examines the role of the Ambonsche Studiefonds and Sarekat Ambon organizations in fostering nationalism among Maluku natives and in the struggle for Indonesian independence.
Sem Touwe   +3 more
doaj   +1 more source

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