Results 131 to 140 of about 245,985 (307)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Kevin Sessums at the Queer History of Fashion Symposium
Kevin Sessums, author and editor in chief of FourTwoNine magazine, presents "The World was Safer Sitting Under my Grandmother's Singer Sewing Machine: A Sissy's Remembrance of a Boyhood Filled with Butterick Patterns and Bouffant Palaver" at The Museum ...
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Exhibiting Fashion Symposium: Marie Riegels Melchior "Fashion and Dress Museology"
The Museum at FIT presented Exhibiting Fashion, its twenty-first academic symposium on Friday, March 8, 2019. This symposium explored the history of fashion curating, the different ways fashion is displayed in museum settings, and how national and ...
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Etnoantropološki ProblemiIn May 2025, the Department of Ethnology and Anthropology at the Faculty of Philosophy, University of Belgrade, organized for the first time a conference dedicated to the analysis of the phenomenon of fashion. The national scientific conference, entitled
Danijela Velimirović
doaj
Dr. Joyce F. Brown introduces the Queer History of Fashion Symposium
Dr. Joyce F. Brown, President of FIT, delivers the welcome remarks at The Museum at FIT's 13th fashion symposium, A Queer History of Fashion, held November 8-9 ...
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Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Etnoantropološki ProblemiIn May 2025, the Department of Ethnology and Anthropology at the Faculty of Philosophy, University of Belgrade, organized for the first time a conference dedicated to the analysis of the phenomenon of fashion. The national scientific conference, entitled
Danijela Velimirović
doaj
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source