Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Emergency superficial temporal artery-superior cerebellar artery bypass for hyperacute basilar artery occlusion following elective middle cerebral artery aneurysm clipping: illustrative case. [PDF]
Andrade Valencia JL +4 more
europepmc +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
The relationship between compulsive shopping behavior, family functioning, and fashion orientation among female students: a descriptive cross-sectional correlational study. [PDF]
Baniashraf F +4 more
europepmc +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Surgical management of petrosal dural arteriovenous fistulas. [PDF]
Kappel AD +4 more
europepmc +1 more source
Immersive Learning: History of Fashion Course
Diana Saiki, Jane Prell
openaire +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Management of type 2 endoleaks following endovascular thoracic aortic dissection repair associated with patent ductus arteriosus: A report of two cases in patients with Marfan syndrome. [PDF]
Burk J +5 more
europepmc +1 more source

