Results 31 to 40 of about 245,985 (307)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The Fortune of the Ancient World’s Heritage Within the Context of Fashion Museums’ Communication in Italy

open access: yesZoneModa Journal, 2022
Demonstrating the contribution and the communicative potential of classics to the history of Italian art and, as a consequence, to the history of Italian fashion is the aim of this paper.
Virginia Spadaccini
doaj   +1 more source

Maroon Fashion History [PDF]

open access: yesNew West Indian Guide / Nieuwe West-Indische Gids, 2020
Abstract Fashion has long been a dynamic aspect of Maroon culture in Suriname and French Guiana (Guyane). The textile arts that carry it through from one generation to the next were totally ignored by early writers, who lavished praise on the men’s art of woodcarving but said virtually nothing about the artistic gifts of women—most importantly in ...
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Atelier picturebook: la moda raccontata nei libri per bambini

open access: yesZoneModa Journal, 2018
An international inquiry about picturebooks included in the exhibition The Extraordinary Library, 100 picturebooks between fashion and wonder selected by Bologna Children’s Books Fair for Pitti Immagine Bimbo 2017 shows the rich fan of possible ...
Silvana Sola, Marcella Terrusi
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Croquis et photographies de la maison Balmain : quels enjeux patrimoniaux ?

open access: yesIn Situ
This contribution sets out to reconsider the importance of the fashion heritage which is comprised of sketch and photo collections, the ‘related’ and complementary items alongside the fashion accessories and clothes themselves.
Julia Guillon
doaj   +1 more source

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