Results 111 to 120 of about 599,885 (312)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

MILITARY HEROIZATION IN THE EPOCH OF WWI: THE RUSSIAN CASE OF FIELD MARSHAL-GENERALISSIMO SUVOROV IN A COMPARATIVE PERSPECTIVE, 1900–1917

open access: yesСучасні дослідження з німецької історії, 2014
The article is devoted to commemoration of A. Suvorov in the Russian empire on the eve of World War I. The author tells about the tradition to erect monuments to the heroes of war, particularly to especially successful military leaders, starting since ...
R. Nachtigal
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

What Germany wants- as diplomacy over Brexit begins [PDF]

open access: yes, 2016
First paragraph: Greece, the refugee crisis, and now Brexit. The German Foreign Office’s first reaction the day after the UK’s vote to leave the EU in a referendum came in the form of a tweet:  We are off now to an Irish pub to get ...
Nehring, Holger
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Традиції германістики у Дніпропетровському університеті в 1970–1990‑х рр. Інтерв’ю із Сергієм Плохієм

open access: yesСучасні дослідження з німецької історії
В інтерв’ю з професором Гарвардського університету C. Плохієм обговорено питання розвитку школи германістики у Дніпропетровському університеті у 1970–1990‑х рр.
A.G. Venher
doaj   +1 more source

History Studies: University of Limerick History Society Vol (14)

open access: yes, 2013
We are pleased to present volume fourteen of History Studies. This editions contains eight essay’s based on the work of both undergraduates and postgraduates students’ in both Irish and British universities.
University of Limerick History Society (12628816)
core  

The Roma Struggle for Compensation in Post-War Germany [PDF]

open access: yes, 2011
Thirty years passed before it was accepted, in West Germany and elsewhere, that the Roma (Germany's Gypsies) had been Holocaust victims. And, similarly, it took thirty years for the West German state to admit that the sterilisation of Roma had been part ...
von dem Knesebeck, Julia
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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