Results 51 to 60 of about 599,885 (312)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Paediatric systemic inflammatory response syndrome (SIRS) and the development of patient-specific therapy: ethical perspectives through experts’ opinions

Frontiers in Public Health
BackgroundResearch for personalised therapies concerning the Systemic Inflammatory Response Syndrome (SIRS) in children involves the utilisation of OMICS technologies and Artificial Intelligence (AI).MethodsTo identify specific ethical challenges through
Frederik Stolte, Silviya Aleksandrova-Yankulovska, Paul Thiemicke, Marcin Orzechowski, Catharina Schuetz, Florian Steger   +5 more
doaj   +1 more source

Restelo in Lisbon - The Non-implementation of the Original Urban Design by Faria da Costa during the Dictatorship of António de Oliveira Salazar [PDF]

, 2015
Beiträge zum Symposium „Urban design and dictatorship in the 20th century: Italy, Portugal, the Soviet Union, Spain and Germany. History and Historiography“. Weimar, 21.-22.
Cravo, Salete A. F.
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Some Sketches for the Portrait of World History Historian in Dnipropetrovsk: M.O. Yuriev in Procrustean bed of Stalin`s Repressions

Сучасні дослідження з німецької історії, 2018
In this article the biography of M. Yuriev has been analyzed. Yuriev was the head of the World History department of Dnipropetrovsk Institute of Public Education and worked at the University at the beginning of 1930-th.
A. G. Venger
doaj   +1 more source

Public History as Graphic History

Graphic History – the telling, teaching and understanding of history through comics – has been growing in classrooms and university spaces for more than two decades. However, in the discipline of history the engagement with comics is still rare.
Gundermann, Christine , Wright, Amie   +1 more
core   +1 more source

Portuguese Social Housing under Dictatorship. A Morphological Analysis of Some Residential Agglomerations in Lisbon (1933-1950) [PDF]

, 2015
Beiträge zum Symposium „Urban design and dictatorship in the 20th century: Italy, Portugal, the Soviet Union, Spain and Germany. History and Historiography“. Weimar, 21.-22.
Cabrita, Maria Amélia
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Troops of the Central States in Ukraine (1918): cases of violations and material damage

Сучасні дослідження з німецької історії, 2018
The purpose of the study is to find out the amount of losses inflicted in 1918 to the Ukrainian treasury and private individuals by Austro-Hungarian and German troops. The research is based on the data that had been collected by Hetman P.
T. V. Malynovska, B. V. Malynovsky
doaj   +1 more source

Travel and the Greek migrant youth residing in West Germany in the 1960s-1970s

, 2014
Volume information: 'Between Leisure, Work, and Study: Tourism and Mobility in Europe from 1945-1989', Nikolaos Papadogiannis (U St. Andrews, UK) and Detlef Siegfried (U Kopenhagen, Denmark), eds., ISBN 978-3-86583-896-4.This article explores the travel ...
Papadogiannis, Nikolaos
core   +1 more source