Results 71 to 80 of about 688,137 (308)

Holisms of communication: The early history of audio-visual sequence analysis

, 2021
A central pillar of contemporary communication research is the analysis of filmed interactions between people. The techniques employed in such analysis first took on a recognizably modern form in the 1970s, but their roots go back to the earliest days of
Ploder, Andrea, Watter, Seth Barry, McElvenny, James, Kendon, Adam, Czwik, Maria, Schmitz, H. Walter, Lück, Helmut E., Leeds-Hurwitz, Wendy, Mondada, Lorenza, Friedrich, Janette, Engelke, Henning, Knobloch, Clemens   +11 more
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Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

The change of the name of the Russian language in Russian from Rossiiskii to Russkii : did politics have anything to do with it? [PDF]

, 2012
During the 1830s and 1840s the official Russian name of the Russian language changed from Rossiiskii to Russkii. Prior to this the names of the country and of its language were directly related (Rossiia – Rossiiskii), while today they remain disjointed ...
Kamusella, Tomasz, Kamusella, Tomasz Dominik   +1 more
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Towards a history of concept list compilation in historical linguistics. History and Philosophy of the Language Sciences [PDF]

, 2018
Blog post, published with the blog "History and Philosophy of the Language Sciences". Here shared in form of a paper draft. Please cite as: List, Johann-Mattis. 2018. Towards a history of concept list compilation in historical linguistics.
Johann-Mattis List
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

BAP502 : Theory and practice of translation (Arabic language) / Academy of Language Studies [PDF]

, 2017
This course emphasises translation disciplines from the theoretical and practical aspects. The theoretical aspect will focus on the development in the field of translation in terms of its history, definition, theories and principles.
UiTM, Academy of Language Studies
core  

Historical phonology of Mataguayan

This book discusses the phonological history of Mataguayan, a language family that includes no less than four distinct languages – Maká, Nivaĉle, Chorote, and Wichí – spoken by ca.
Nikulin, Andrey, Carol, Javier
core   +6 more sources