Results 21 to 30 of about 241,605 (215)

Everyday Ethnocultural Adaptation of Newly Arrived and Indigenous Populations in Yugra

open access: yesSHS Web of Conferences, 2018
This publication presents results of a study of everyday ethnocultural adaptation of newly arrived and indigenous populations in Khanty-Mansi Autonomous Okrug – Yugra.
Tkachev Boris   +3 more
doaj   +1 more source

History for Pure Life: Reviewing the Effects of World and Islamic History on Ethics. [PDF]

open access: yesInternational Multidisciplinary Journal of Pure Life
SUBJECT & OBJECTIVES: Understanding the impact of world history on ethics is crucial for fostering global ethical discourse and navigating modern challenges with historically informed moral decisions.METHOD & FINDINGS: The study finds that world history ...
Amir Karimi   +3 more
doaj   +1 more source

The Contradictions of Saint Paul’s Cathedral

open access: yesARCHive-SR, 2023
Saint Paul’s Cathedral is a contradiction. Beautiful and majestic, it combines an almost Catholic shape with a Protestant soul. It is one of the most powerful symbols of England, and a reason for pride for any Londoner.
Ilaria Bortot, Harry Ellerd-Cheers
doaj   +1 more source

The Potential of AI Image Generation (Bing Platform) and Its Impact on Improving History Education: A Case Study of 11th Grade History with Emphasis on the Lesson "Islam in Mecca [PDF]

open access: yesتاریخ نگری و تاریخ نگاری
In traditional history education, dry and memorization-based narratives often focus solely on the mere transmission of information and subjective analyses, which can reduce student motivation and limit their deep, multifaceted understanding.
Maryam Khosroabadi, Milad Ajami
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

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