Results 61 to 70 of about 1,742,386 (312)

A Study of the Role of the Education System and Arab Nationalists in Propagating the Ideology of Nationalism in Iraq (1921-1941) [PDF]

open access: yesپژوهش های تاریخی, 2019
Since its establishment in 1921, Iraq’s borders were incorporated by a diverse medley of people who had not been joined into a single political community with a common sense of identity.
Shokrollah Khakrand, siavash yadollahi
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The Heart of Librarianship: A Literature Review of Outreach in Academic Libraries

open access: yes, 2021
Presentation that provides a summary of the literature on library outreach and indicates how the literature review has impacted outreach developments at the UNT Libraries.
Henson, Brea
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Literature for primary school and education of republican citizens, in the Revista de Ensino (SP-Brazil) - 1902-1918

open access: yes, 2015
Aiming to contribute to the understanding of unexplored aspects of the history of children's literature, of the history of the teaching of reading, and of education in Brazil, this paper focuses on the section Children's Literature (or similar names) of ...
Longo Mortatti, Maria do Rosario [UNESP]
core   +1 more source

И. С. Гал­кин  90 [I. S. Galkin  90] [PDF]

open access: yesLinguistica Uralica, 1970
Valerij Maksimov   +4 more
doaj   +1 more source

History of Poland during the Middle Ages [PDF]

open access: yes, 2015
The present book “Poland – History, Culture and Society. Selected Readings” is the third edition of a collection of academic texts written with the intention to accompany the module by providing incoming students with teaching materials that will assist ...
Kowalska-Pietrzak, Anna
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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