Results 101 to 110 of about 3,956,965 (389)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Doctor Nurys Diéguez Andrés (1951-2016), mainstay of the Intensive Care Medicine in Las Tunas

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016
Doctor Nurys Nirma Diéguez Andrés is one of the outstanding personalities in the barely four decades of universal and free medicine in the Cuban province of Las Tunas. She started her graduate studies on Internal Medicine at Dr.
Orlando Rafael Serrano Barrera
doaj  

A sociological approach to the history of medicine.

open access: yesMedicina e historia, 1970
WHAT HISTORY can teach is a much-discussed question and historians themselves are divided about the answer; what medical history can teach is a question which is not often asked and yet there can be little doubt about the answer. The direction of medical
T. Mckeown
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Infezioni [PDF]

open access: yesS&F_scienzaefilosofia.it, 2015
We will analyze a segment of the very complex theoretical background concerning the current History of Medicine. In this sense, it is indispensable to examine the social contextualization of medicine, its links to political and cultural history, i.e.
Amodio, Paolo
doaj  

History of evidence-based medicine

open access: yesIndian Journal of Urology, 2011
This essay reviews the historical circumstances surrounding the introduction and evolution of evidence-based medicine. Criticisms of the approach are also considered.
Roger L Sur, Philipp Dahm
doaj   +1 more source

Recycling the evidence: different approaches to the reanalysis of gerontological data [PDF]

open access: yes, 2005
In 1991 Professor Margot JEFFERYS and two colleagues interviewed "pioneers of geriatric medicine" of whom 60 were geriatricians. These data are now on disk and can be searched digitally. The interviews were long and focussed on the careers of the doctors
Bornat, Joanna
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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