Results 271 to 280 of about 931,837 (389)

Population pharmacokinetics and optimized dosing of cefuroxime in critically ill patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Cefuroxime is a second‐generation cephalosporin widely used in the intensive care unit (ICU). ICU patients have high variability in interpatient pharmacokinetics (PK), but the extent of this variation is unclear. We performed an observational PK study in ICU patients.
Jaap W. A. Mouton   +9 more
wiley   +1 more source

Trends in drug–drug interaction prevalence and longitudinal associations with health outcomes in the older community‐dwelling population: Findings from The Irish LongituDinal study on Ageing

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims We estimate trends in severe drug–drug interaction (DDI) prevalence and examine longitudinal associations between DDI exposure and health outcomes (emergency department [ED] visits, quality‐of‐life [QoL] and functional decline) over approximately 10‐years in the older community‐dwelling population in Ireland.
John E. Hughes   +2 more
wiley   +1 more source

Mental suffering, based on the experiences of people who are mentally ill. [PDF]

open access: yesPrim Health Care Res Dev
Ventura CAA   +4 more
europepmc   +1 more source

Trends in opioid prescribing in Scandinavian countries from 2010 to 2023: Insights from multi‐metric evaluation

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Monitoring opioid prescribing across different healthcare systems is essential to understanding population‐level exposure and informing global health policies. This study examined opioid utilization in Scandinavian countries between 2010 and 2023 using multiple complementary metrics, addressing the limitations of single‐metric comparisons ...
Gabriela Rolová   +6 more
wiley   +1 more source

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