Results 171 to 180 of about 317,424 (303)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Risk Stratification of Penicillin Allergy Labeled Children: A Cross-Sectional Study from Jordan

open access: yesTherapeutics and Clinical Risk Management
Jomana W Alsulaiman,1 Khalid A Kheirallah,2 Ahmad Alrawashdeh,3 Tareq Saleh,4 Maha Obeidat,5 Yareen J Alawneh,2 Ziydoun Abu Sanad,5 Wajdi Amayreh,1 Rama J Alawneh2 1Department of Pediatrics, Faculty of Medicine, Yarmouk University, Irbid, Jordan ...
Alsulaiman JW   +8 more
doaj  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Research progress on application of metagenomics technology in animal production

open access: yesSiliao yanjiu
Macrogenomics technology is a core omics method that systematically analyzes the composition, function, and ecological relationships of microbial communities by studying the entire microbial genome in the environment through high-throughput sequencing ...
ZHANG Jinbao   +4 more
doaj  

Evaluation of <i>XRCC4</i> and <i>VEGF</i> Gene Variants in Relation to Breast Cancer Risk in a Jordanian Cohort. [PDF]

open access: yesCancer Manag Res
Al-Eitan L   +6 more
europepmc   +1 more source

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