Results 41 to 50 of about 180,398,810 (309)
Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz +12 more
wiley +1 more source
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani +7 more
wiley +1 more source
For the past 150 years, Science has become central to public issues, arbitrating all aspects of human life and defining what is natural and rational. Teaching the history of science by emphasising its dynamics as a social institution and the resulting ...
Ana Barahona +9 more
doaj +1 more source
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben +4 more
wiley +1 more source
The History of Science Section and the Progress of Science [PDF]
n ...
openaire +3 more sources
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
SOCIETAS PHYSICAE EXPERIMENTALIS – THE FIRST PHYSICS SOCIETY IN POLAND. THE ORIGINS OF THE SOCIETY
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ANDRZEJ JANUSZAJTIS
doaj
The Rise, Decline and Migration of Science in the Dutch Republic and the Spanish Netherlands Science in the Southern and Spanish Netherlands flourished in the sixteenth century, whereas the hey-day of science in the Northern Netherlands (or the Dutch ...
A. de Bruycker, D. van Netten
doaj +1 more source
Science and History of Science
In the present article, we discuss the specificity of the object of the history of science as an autonomous and interdisciplinary field of studies by nature and origin, placed at the interface of history, epistemology and science, and focus on some key historiographical views. Within this context, Georges Canguilhem stands out for contributions such as
Ferraz, Márcia H. M. +2 more
openaire +3 more sources
Toward a Science of History [PDF]
The scientific status of History was compared to other sciences in the critical areas event selection, investigative operations, and theory construction. First, in terms of events studied, history is regarded as a quasi-scientific study of past events.
L J, Parrott, D F, Hake
openaire +2 more sources

