Results 231 to 240 of about 1,201,984 (318)

Autoimmune Gastritis in Children: A Rare Cause of Refractory Iron-Deficiency Anemia. [PDF]

Reports (MDPI)
Lendínez-Jurado A, García-Ruiz A, Sastre-Domínguez MA, Vallejo-Benítez AM, Scavarda-Lamberti A, Navas-López VM.   +5 more
europepmc   +1 more source

Flexible and High‐Performance Perovskite‐Polymer Composites for Dual X‐Ray and Proton Direct Detection

Advanced Optical Materials, EarlyView.
A polymer–perovskite composite obtained by mechanochemical synthesis enables thick, tunable active layers for efficient absorption of highly penetrating ionizing radiation. Vertical‐electrode detectors achieve low X‐ray detection limits and high sensitivity direct 5 MeV proton sensing.
Camilla Bordoni, Bas A. H. Huisman, Joost W. C. Reinders, Ilaria Fratelli, Massimo Chiari, Laura Basiricò, Henk J. Bolink, Andrea Ciavatti, Michele Sessolo, Beatrice Fraboni   +9 more
wiley   +1 more source

Pathways to chronic benzodiazepine use: a qualitative study of user and professional perspectives. [PDF]

BMC Prim Care
Peñarrubia-Maria MT, Olmos-Palenzuela MC, Gil-Girbau M, Rubio-Valera M, Puig-García M, Guilabert Mora M, López-Pintor E, Rosell EC, Parker LA, Aznar-Lou I.   +9 more
europepmc   +1 more source

Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinositol Signaling to Histone Methylation

Advanced Science, EarlyView.
Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater, Savvas Kourtis, Camilla Reiter Elbæk, Lorena Espinar, Carolina Toro‐Márquez, Albert Coll‐Manzano, Alfredo Smiriglia, Laura García‐López, Laura Wiegand, Maria Guirola, Frédéric Fontaine, Andrea Morandi, André C. Müller, Sara Sdelci   +13 more
wiley   +1 more source

Real-world data of opicapone in patients with Parkinson's disease experiencing motor fluctuations: the OPTIMO study. [PDF]

Front Neurol
Luquin MR, Lopez-Ariztegui N, Castrillo JCM, Manzanares LL, Bataller IS, Fernández AK, Pastor BV, Vila BS, Sauco MÁ, Mora JP, González JMA, Ruiz-Espiga PJG, de Fàbregues O, Del Val JL, Arillo VC, Moreno C, Ameijeiras JB, Jiménez IP, Ayuela IT.   +18 more
europepmc   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Participant selection for lung cancer screening using primary care electronic medical records: The Catalan scenario. [PDF]

Aten Primaria
Marzo-Castillejo M, Mascort Roca J, Brau Tarrida A, Carrasco Ribelles L, Monteagudo Zaragoza M, Guiriguet Capdevila C, Espinàs Piñol JA, Cabrera Godoy O, Borras Andrés JM.   +8 more
europepmc   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

Advanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda, Ada Bernaus Vives, Michał Wojciechowski, Dinh Quoc Huy Pham, Mateusz Chwastyk, Mario Vallejo, Anna Novials, Douglas V. Laurents, Mariano Carrión‐Vázquez   +8 more
wiley   +1 more source

Cardiac findings and observation duration in patients with syncope in the emergency department: a cohort study. [PDF]

BMC Emerg Med
Carbonel-Tabuenca A, López-Sobrino T, Vilurbina-Pérez P, Andujar-Lara I, Cararach-Salami D, Ayala-Borges B, Szlendak L, Castrillo-Golvano L, González-de Paz L.   +8 more
europepmc   +1 more source

Climate Change Threatens Micronutrient Density of European Winter Wheat

Advanced Science, EarlyView.
Micronutrients are vital for human health. Wheat is a major staple crop and a significant source of minerals and B‐vitamins. The impact of climate change on their content remains largely unknown. We evaluated micronutrient levels in European winter wheat grown under historical and projected climate conditions. Our findings indicate that future climates
Da Cao, Jennifer Michel, Eline Lorer, Markus Weinmann, Jacques Le Gouis, Claire Léon, Sibille Perrochon, David Alvarez, Vincent Leemans, Iñaki Balanzategui Guijarro, Jordi Moya Laraño, Sara Sánchez Moreno, Symanczik Sarah, Waibel Matthias, Hervé Vanderschuren, Cécile Thonar, Pierre Delaplace, Dominique Van Der Straeten   +17 more
wiley   +1 more source