Results 21 to 30 of about 787,743 (263)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Railway photography and technology: analysis of the photographic record of Brazilian railway in the 19th century [PDF]
História, 2019 The purpose of this text is to examine some sets of photographs about railway companies in Brazil, in order to highlight the potential of this type of iconographic material, not as artistic documentation but also technological documentation.
Eduardo Romero de Oliveira
doaj +3 more sources
Історія науки і техніки, 2022 World War I proved air forces to be a critical driver for warfare outcomes. Mastery of the latest technology appeared to be crucial to the battle’s success.
Liudmyla Vaniuha +4 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Osmanlı Devleti’nde İletişim Araçlarının Kontrolü: “Telefon Tevkifleri”
Osmanli Bilimi Arastirmalari, 2020 On dokuzuncu yüzyılın bilim ve teknik alanındaki başlıca icatlarından biri telefondur. 1875’teki icadından sonra dünya ülkelerine hızla yayılmıştır. Osmanlılar, patenti Alexander Graham Bell tarafından 1876’de alınan telefon ile II. Abdülhamid döneminde,
Şeyhmus Bi̇ngül
doaj
Development of the oil industry in the USA in the 20th century (Part II)
Cхід, 2019 The article looks into the history of the oil and gas industry which has been dynamically developing today. Oil and natural gas as well as their processing products have a very long history of use by mankind though the history of the world oil industry ...
Gennadiy Gayko, Volodymyr Biletsky
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source