Results 151 to 160 of about 178,378,615 (312)

Visibility of the Massachusetts Institute of Technology entrepreneurship ecosystem : MIT undergraduate awareness of on-campus entrepreneurship resources

open access: yes, 2012
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2012.This electronic version was submitted by the student author.
Cheng, Kuan, S.B. Massachusetts Institute of Technology
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Re-humanizing the distributed infrastructures of Bitcoin

open access: yes, 2019
This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Thesis: S.M., Massachusetts Institute of Technology, Department of Architecture, 2019Cataloged from PDF ...
Wu, Yue,S.M.Massachusetts Institute of Technology.
core  

Sara Jervis and Derek Whitehead, 50th Anniversary of IBL, 2013

open access: yes, 2013
Sara Jervis (Coordinator, Swinburne History and Artefacts) and Derek Whitehead (Director, Information Technology Services) at 50th anniversary of Industry Based Learning (IBL) celebrations, ATC Building, Hawthorn Campus, 18 July ...
Swinburne University of Technology
core   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Strategies for transformation of Linpan countryside of Chengdu plain, China

open access: yes, 2014
Thesis: S.M., Massachusetts Institute of Technology, Department of Architecture, June 2014.This electronic version was submitted by the student author.
Hong, Fei, S.M. Massachusetts Institute of Technology
core  

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

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