Results 141 to 150 of about 178,378,615 (312)
Vaccines in veterinary medicine: a brief review of history and technology. [PDF]
Vet Clin North Am Small Anim Pract, 2010 McVey S, Shi J.
europepmc +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Analysis of merger and acquisition frameworks from a deal rationale perspective in technology sector
, 2019 Thesis: S.M. in Engineering and Management, Massachusetts Institute of Technology, System Design and Management Program, 2019Cataloged from PDF version of thesis.Includes bibliographical references.Mergers and Acquisitions (M&A) activity has been a ...
Narayanan, Sridhar,S.M.Massachusetts Institute of Technology.
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Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Exploration of generative adversarial network in site plan / floorplan generation
, 2020 Thesis: M. Arch., Massachusetts Institute of Technology, Department of Architecture, February, 2020Cataloged from student-submitted thesis.Includes bibliographical references (pages 99-100).Technology has always been an important factor that shapes the ...
Wu, Chaoyun,M. ArchMassachusetts Institute of Technology.
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Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
To Copy, To Impress, To Distribute: The Start of European Printing
On_Culture, 2019 In order to distribute our thoughts and feelings, we must make intelligible and distributable copies of them. From approximately 1375 to 1450, certain Europeans started fully mechanized replication of texts and images, based on predecessor “smaller ...
Bennett Gilbert
doaj
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Investigation into the use of surface-enhanced Raman spectroscopy (SERS) for organic dye analysis
, 2015 Thesis: S.B., Massachusetts Institute of Technology, Department of Materials Science and Engineering, 2015.Cataloged from PDF version of thesis.Includes bibliographical references (pages 48-49).In art conservation, color is essential to understanding a ...
Lin, Sally, S.B. Massachusetts Institute of Technology
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Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source