Results 41 to 50 of about 175,139,164 (218)

Numérique et humanités : de l’ancillarité à la fécondité grâce à la modélisation computationnelle des connaissances

open access: yesHumanités Numériques, 2023
The digital transformation of society also affects the humanities and social sciences (HSS). The digital humanities follow the general pattern of digital history, which we will briefly describe.
Yannis Delmas-Rigoutsos
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Public Electricity Supply in Portuguese Guinea, 1930-1974

open access: yesHoST
Guinea-Bissau has a chronically underperforming electricity sector that fails to provide most of the population outside of the capital, Bissau, with access to electricity – nowadays considered a basic human need.
Stoppok Manfred
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Alographia dos álkalis... de Frei Conceição Veloso: um manual de química industrial para produção da potassa no Brasil colonial The production of potash from plants in colonial Brazil as described in fray Conceição Veloso's Alographia dos alkalis...

open access: yesQuímica Nova, 2008
Potassium carbonate, or potash, was the most important industrial chemical of the 18th century. It was essential for producing glass, soap, saltpeter, dyes, several drugs, and also used for bleaching linens, paper, and sugar.
Fernando J. Luna
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Characterizing radio channels : the science and technology of propagation and interference, 1900-1935 [PDF]

open access: yes, 2004
Thesis (Ph. D. in History and Social Study of Science and Technology (HASTS))--Massachusetts Institute of Technology, Program in Science, Technology and Society, 2004.Includes bibliographical references (p.
Yeang, Chen-Pang.
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Transition to smart card technology : how transit operators can encourage the take-up of smart card technology [PDF]

open access: yes, 2006
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, 2006.Includes bibliographical references (p. 181-184).This thesis explores and evaluates the essential strategies needed for transit agencies to switch ...
Hong, Yi, S.M. Massachusetts Institute of Technology
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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