Results 61 to 70 of about 782,357 (263)

The Electrification of Tramways in Ostrava in 1900–1901

Acta Polytechnica, 2012
This paper focuses on the electrification of tramways in Ostrava in 1900-1901. As the administrative, economic and cultural centre of an evolving industrial agglomeration, Ostrava had specific transportation requirements.
Michaela Závodná
doaj  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Introduction: History from Underneath the Surface: Diving and Submarine Environments since the Nineteenth Century

Journal for the History of Environment and Society
The introduction to this special issue of the Journal for the History of Environment and Society argues that diving has been and remains a crucial practice for experiencing the sea, studying the underwater environment, and exploiting life and resources ...
Eike-Christian Heine
doaj   +1 more source

Flourishing tumor organoids: History, emerging technology, and application. [PDF]

Bioeng Transl Med, 2023
Yang Q, Li M, Yang X, Xiao Z, Tong X, Tuerdi A, Li S, Lei L.   +7 more
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Wireless Telegraphy at the German Universal Exhibition in Ústí nad Labem in 1903 [1]

Acta Polytechnica, 2008
This paper focuses on the transmission of wireless telegraphy between Ústí nad Labem and Teplice during the German Universal Exhibition in Ústí nad Labem in 1903.
T. Okurka
doaj  

Techno-Optimism Archive: Technological Optimism, Utopianism, Solutionism, and Hype in the Historical Press

Journal of Open Humanities Data
The Techno-Optimism Archive Dataset is a curated collection of historical press examples of technological optimism and techno-solutionist thought. Drawn from dispersed digital archives of newspapers and magazines, it captures recurring promises that ...
Krystian Łukasik
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source