Results 41 to 50 of about 787,743 (263)
Potassium carbonate, or potash, was the most important industrial chemical of the 18th century. It was essential for producing glass, soap, saltpeter, dyes, several drugs, and also used for bleaching linens, paper, and sugar.
Fernando J. Luna
doaj +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Making the History of Computing. The History of Computing in the History of Technology and the History of Mathematics [PDF]
Abstract A history of writing the history of computing is presented in its relationship to the history of mathematics. As with many historiographies, the initial history of computing was very much an internalistic history. In the late 1970s, the field became more serious and started looking at the histories of mathematics and technology for ...
de Mol, Liesbeth, Bullynck, Maarten
openaire +2 more sources
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
The circulation of British engineers in South America during the first half of the twentieth century is a barely explored phenomenon that should be studied in the basis of methodologies that articulate the different elements involved, with the aim of ...
Jorge Alonso Rodríguez Ortiz
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The History of Science in Latin America in its own terms
This article conducts a comparative analysis of two journals: Quipu, created in 1984 by the Latin American Society for the History of Sciences and Technology in Mexico, published until 1994 and shortly relived between 1999 and 2000, and the Brazilian ...
Marcia Regina Barros da Silva
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Beyond Innovation and Use, or Why We Must Follow Technologies through Time
Synthesizing various studies that follow technology beyond innovation and use, this article aims to continue widening the scope of history of technology toward this perspective. It argues that we must follow technology through time and—in addition to its
Heike Weber
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