Results 111 to 120 of about 175,139,164 (218)
, 2020 Thesis: Ph. D., Massachusetts Institute of Technology, Department of Physics, February, 2020Cataloged from PDF version of thesis.Includes bibliographical references (pages 207-233).With over 4000 exoplanets already confirmed and more to come through ...
Guo, Xueying,Ph. D.Massachusetts Institute of Technology.
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Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Courtroom characters, architectural actors : a play in several acts
, 2015 Thesis: M. Arch., Massachusetts Institute of Technology, Department of Architecture, 2015.Cataloged from PDF version of thesis.Includes bibliographical references (page 65).This thesis takes aim at several agendas within architectural discourse.
White, Robert O., M. Arch Massachusetts Institute of Technology
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
The return of the infrastructure "Muti-Platform City"
, 2016 Thesis: S.M., Massachusetts Institute of Technology, Department of Architecture, 2016.Page 157 blank. Cataloged from PDF version of thesis.Includes bibliographical references (pages 143-147).Cities, spaces that always coexist with the old and new, are ...
Lee, Byongjun, S.M. Massachusetts Institute of Technology
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The first educational exodus : a narrative of 1965 [PDF]
, 2013 Thesis (S.B. in History)--Massachusetts Institute of Technology, Dept. of Humanities, 2013.Cataloged from PDF version of thesis.Includes bibliographical references (p. 68-71).Histories of Boston's school desegregation crisis have focused on the legal and
Huang, Billy
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Under the historian’s radar: Local water-supply practices in Nairobi, 1940-1980
Water Alternatives, 2020 By presenting oral history material from two informal settlements in Nairobi, Kenya, the article illustrates how inhabitants during the period 1940 to 1980 acquired and used water on a daily basis.
Jethron Ayumbah Akallah, Mikael Hård
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A design strategy for transforming an old power plant into a cultural center [PDF]
, 2009 Thesis (M. Arch.)--Massachusetts Institute of Technology, Dept. of Architecture, 2009.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from student-
Park, Sung-o, M. Arch. Massachusetts Institute of Technology
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source