Results 51 to 60 of about 782,357 (263)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Beyond Innovation and Use, or Why We Must Follow Technologies through Time

Histories
Synthesizing various studies that follow technology beyond innovation and use, this article aims to continue widening the scope of history of technology toward this perspective. It argues that we must follow technology through time and—in addition to its
Heike Weber
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

What Were Bulletin Board Systems? Looking Back At Pre-Internet Online Communication in Turkey

İletişim Kuram ve Araştırma Dergisi
As an online communication technology predating the Internet, Bulletin Board Systems (BBSs) are considered to be precursors of modern-day social media. Despite being a popular technology of its era both in Türkiye and abroad, BBS technologies tend to be ...
Ivo Ozan Furman
doaj   +1 more source

Self-Writing Machines: Technology and the Question of the Self

communication +1, 2015
In order to show that technology mediates between man and machine, I will discuss in this text a literally other or alter-knowledge system that also heavily relied on self-writing machines: spiritualism.
Christian Kassung
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

How to Activate the Potential of Imaginary Networks

VIEW Journal of European Television History and Culture
I explore how imaginary networks provide us with meaningful models for alternative future networks outside of or beyond the internet. This essay mostly looks first at how media archaeology’s interest in uncovering media from the past to reimagine media ...
Lori Emerson
doaj   +1 more source

History of Technology [PDF]

Nature, 1955
A History of Technology Edited by Charles Singer, E. J. Holmyard and A. R. Hall; assisted by E. Jaffe, R. H. G. Thomson and J. M. Donaldson. Vol. 1: From Early Times to Fall of Ancient Empires. Pp. lv + 8 maps + 828 + 36 plates. (Oxford: Clarendon Press; London: Oxford University Press, 1954.) £7 7s. net.
openaire   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source