Results 21 to 30 of about 815,920 (262)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Історія науки і техніки, 2022 World War I proved air forces to be a critical driver for warfare outcomes. Mastery of the latest technology appeared to be crucial to the battle’s success.
Liudmyla Vaniuha +4 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Osmanlı Devleti’nde İletişim Araçlarının Kontrolü: “Telefon Tevkifleri”
Osmanli Bilimi Arastirmalari, 2020 On dokuzuncu yüzyılın bilim ve teknik alanındaki başlıca icatlarından biri telefondur. 1875’teki icadından sonra dünya ülkelerine hızla yayılmıştır. Osmanlılar, patenti Alexander Graham Bell tarafından 1876’de alınan telefon ile II. Abdülhamid döneminde,
Şeyhmus Bi̇ngül
doaj
Development of the oil industry in the USA in the 20th century (Part II)
Cхід, 2019 The article looks into the history of the oil and gas industry which has been dynamically developing today. Oil and natural gas as well as their processing products have a very long history of use by mankind though the history of the world oil industry ...
Gennadiy Gayko, Volodymyr Biletsky
doaj +1 more source
Railway photography and technology: analysis of the photographic record of Brazilian railway in the 19th century [PDF]
História, 2019 The purpose of this text is to examine some sets of photographs about railway companies in Brazil, in order to highlight the potential of this type of iconographic material, not as artistic documentation but also technological documentation.
Eduardo Romero de Oliveira
doaj +3 more sources
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source