Results 61 to 70 of about 921,230 (313)

History of Technology [PDF]

open access: yesNature, 1955
A History of Technology Edited by Charles Singer, E. J. Holmyard and A. R. Hall; assisted by E. Jaffe, R. H. G. Thomson and J. M. Donaldson. Vol. 1: From Early Times to Fall of Ancient Empires. Pp. lv + 8 maps + 828 + 36 plates. (Oxford: Clarendon Press; London: Oxford University Press, 1954.) £7 7s. net.
openaire   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Reconstructing the invention of the wheel using computational structural analysis and design

open access: yesRoyal Society Open Science
The invention of the wheel is widely credited as a pivotal moment in human history, yet the details surrounding its discovery are shrouded in mystery. There remains no scholarly consensus on key questions such as where, how and by whom this technology ...
Lee R. Alacoque   +2 more
doaj   +1 more source

Development of the oil industry in the USA in the 20th century (Part II)

open access: yesCхід, 2019
The article looks into the history of the oil and gas industry which has been dynamically developing today. Oil and natural gas as well as their processing products have a very long history of use by mankind though the history of the world oil industry ...
Gennadiy Gayko, Volodymyr Biletsky
doaj   +1 more source

Ethnography of reproductive travel from Turkey to Northern Cyprus [PDF]

open access: yes, 2019
Thesis: Ph. D. in History, Anthropology, and Science, Technology and Society (HASTS), Massachusetts Institute of Technology, Program in Science, Technology and Society, 2019Cataloged from PDF version of thesis.Includes bibliographical references (pages ...
Mutlu, Burcu,Ph. D.Massachusetts Institute of Technology.
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Automatic intrusion recovery with system-wide history [PDF]

open access: yes, 2014
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2014.Cataloged from PDF version of thesis.Includes bibliographical references (pages 67-71).Compromises of our computer systems are ...
Kim, Taesoo, Ph. D. Massachusetts Institute of Technology
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Swinburne College of Technology Faculty of Business Studies handbook, 1973 [PDF]

open access: yes, 1973
Swinburne College of Technology Faculty of Business Studies handbook including general information, course descriptions and subject details for the year ...
Swinburne College of Technology
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

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