Results 51 to 60 of about 815,920 (262)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

What Were Bulletin Board Systems? Looking Back At Pre-Internet Online Communication in Turkey

İletişim Kuram ve Araştırma Dergisi
As an online communication technology predating the Internet, Bulletin Board Systems (BBSs) are considered to be precursors of modern-day social media. Despite being a popular technology of its era both in Türkiye and abroad, BBS technologies tend to be ...
Ivo Ozan Furman
doaj   +1 more source

Self-Writing Machines: Technology and the Question of the Self

communication +1, 2015
In order to show that technology mediates between man and machine, I will discuss in this text a literally other or alter-knowledge system that also heavily relied on self-writing machines: spiritualism.
Christian Kassung
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

How to Activate the Potential of Imaginary Networks

VIEW Journal of European Television History and Culture
I explore how imaginary networks provide us with meaningful models for alternative future networks outside of or beyond the internet. This essay mostly looks first at how media archaeology’s interest in uncovering media from the past to reimagine media ...
Lori Emerson
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The Electrification of Tramways in Ostrava in 1900–1901

Acta Polytechnica, 2012
This paper focuses on the electrification of tramways in Ostrava in 1900-1901. As the administrative, economic and cultural centre of an evolving industrial agglomeration, Ostrava had specific transportation requirements.
Michaela Závodná
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Flourishing tumor organoids: History, emerging technology, and application. [PDF]

Bioeng Transl Med, 2023
Yang Q, Li M, Yang X, Xiao Z, Tong X, Tuerdi A, Li S, Lei L.   +7 more
europepmc   +1 more source

Introduction: History from Underneath the Surface: Diving and Submarine Environments since the Nineteenth Century

Journal for the History of Environment and Society
The introduction to this special issue of the Journal for the History of Environment and Society argues that diving has been and remains a crucial practice for experiencing the sea, studying the underwater environment, and exploiting life and resources ...
Eike-Christian Heine
doaj   +1 more source