Results 121 to 130 of about 288,906 (303)
Introduction to Forum: The Hemispheric French Atlantic [PDF]
“The Hemispheric French Atlantic” begins to suture a transatlantic to a hemispheric spatiality by tracing out the movement of texts, figures, and traditions within a complex and kinetic circulatory system that moves beyond the geometric model imagined by
Burnham, Michelle
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
User adoption of a CRM-based information system within a financial services organisation: An empirical analysis [PDF]
Financial Services firms require processes and systems which can support and maintain customer-related information for the purposes of core business-focussed activity.
Irani, Z, Sharif, AM
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
An Anthropological Perspective on Magistrate Jelderks’ Kennewick Man Decision [PDF]
The “Kennewick Man” controversy is an extremely important case in the history of American anthropology. As anthropologists with backgrounds in American Indian studies and American archaeology, we have a particular interest in this case.
Jones, Peter N., Stapp, Darby
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Accounting for the great divergence [PDF]
This paper “accounts” for the Great Divergence between Europe and Asia in two ways. In the sense of measurement: (1) the traditional view, in which the Great Divergence had late medieval origins and was already well under way during the early modern ...
Broadberry, S. N.
core
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
“We Wear the Mask”: Kongo Folk Art and Ritual in South Carolina
This article argues for a vision of the African diaspora as an arena of “insurgent nostalgia,” a restive remembrance and embodiment of the past. Blacks throughout the diaspora reconstituted and reconfigured elements of African culture through a series of
Jason Young
doaj
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source

