Results 231 to 240 of about 290,443 (306)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Genomic epidemiology of a 2023-2024 Oropouche virus disease outbreak in Iquitos, Peru: descriptive analysis of a case control study for acute febrile illness. [PDF]

Lancet Reg Health Am
Paredes Olortegui M, Schiaffino F, Peñataro Yori P, Colston JM, Mourkas E, Shapiama Lopez WV, Pinedo Vasquez TN, Garcia Bardales PF, Flynn TG, Ramal-Asayag C, Hughes HR, Davis E, Russell BJ, Brault AC, Alegre Palomino YA, Munayco CV, Liu J, Houpt E, Pascoe B, Cooper KK, Parker CT, Kosek MN.   +21 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Mental health and quality of life of migrants in transit through the Darién gap: A cross-sectional assessment in Panama. [PDF]

J Migr Health
Pinzón-Espinosa J, Erausquin JT, Flores Millender E, Rincón T, Cabezas Talavero G, Franco-Paredes C, Cardoner N, Xavier Hall CD, Wong FY, Wang L, Alvarez C, Gabster A.   +11 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Detection of Aedes (Fredwardsius) vittatus Mosquitoes, Yucatán Peninsula, Mexico, 2025. [PDF]

Emerg Infect Dis
Chan-Chable RJ, Rodríguez-Luna CR, Espinal-Palomino R, Ibarra-Cerdeña CN.   +3 more
europepmc   +1 more source

Interdisciplinary Management of White Coat Hypertension in Geriatric Oral Surgery: Case Report. [PDF]

Geriatrics (Basel)
Allaica Cuenca A, Balseca Morales A, López Bundschuh J, Chauca-Bajaña L, Velasquez Ron B.   +4 more
europepmc   +1 more source

The global outbreak of Oropouche virus: surveillance of global trends. [PDF]

Trop Dis Travel Med Vaccines
Sharma R, Sharma K, Balusamy B, Malviya R, Sivasankaran A, Sundram S.   +5 more
europepmc   +1 more source

Founding Choices: American Economic Policy in the 1790s [PDF]

Robert A. Margo, Stanley L. Engerman
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