Results 81 to 90 of about 289,724 (344)

Analysis of the human Y-chromosome haplogroup Q characterizes ancient population movements in Eurasia and the Americas [PDF]

, 2019
Background: Recent genome studies of modern and ancient samples have proposed that Native Americans derive from a subset of the Eurasian gene pool carried to America by an ancestral Beringian population, from which two well-differentiated components ...
Achilli, Alessandro, Battaglia, Vincenza, Capodiferro, Marco Rosario, Colombo, Giulia, Cruciani, Fulvio, Ferretti, Luca, Grugni, Viola, Motta, Jorge, Olivieri, Anna, Ongaro, Linda, Perego, Ugo A., Raveane, Alessandro, Semino, Ornella, Torroni, Antonio, Tribaldos, Maribel, Trombetta, Beniamino, Woodward, Scott R.   +16 more
core   +7 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Breve história da hanseníase: sua expansão do mundo para as Américas, o Brasil e o Rio Grande do Sul e sua trajetória na saúde pública brasileira Trajectory in the Brazilian Public Health

Saúde e Sociedade, 2004
Este trabalho faz uma revisão sobre a história da hanseníase através dos tempos, desde sua provável origem na Antigüidade até a sua vinda para as Américas, o Brasil e o Rio Grande do Sul.
Letícia Maria Eidt
doaj   +1 more source

Geography is not Destiny. Geography, Institutions and Literacy in England, 1837-1863 [PDF]

Geography made rural society in the south-east of England unequal. Economies of scale in grain growing created a farmer elite and many landless labourers.
Gregory Clark, Rowena Gray
core  

Race, Gender, Sexuality, and Religion in North America [PDF]

, 2017
The history of religion in the United States cannot be understood without attending to histories of race, gender, and sexuality. Since the 1960s, social and political movements for civil rights have ignited interest in the politics of identity ...
Petro, Anthony
core   +1 more source

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Romani American history: Historical absences and their consequences

Romani Studies
American historians have created an historical absence by ignoring Romani people’s presence in evidence from the past. The origins of this “absence-ing” are multifaceted and interrelated, but fundamentally stem from the continued influence of out-of-date
ANN OSTENDORF
doaj   +1 more source

Building "Nuestra América:" national sovereignty and regional integration in the americas

Contexto Internacional, 2013
This article explores the history of regional integration in the Americas, drawing lessons from the diverse ways that people have sought to unite the hemisphere.
Renata Keller
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source