Results 151 to 160 of about 10,473,577 (342)

Probing the gauge symmetry breaking of the early universe in 3-3-1 models and beyond by gravitational waves

, 2018
Taking the 3-3-1 models (with $SU(3)_c \otimes SU(3)_L \otimes U(1)_Y$ gauge group) as examples, we study that a class of new physics models with extended gauge group could undergo one or several first-order phase transitions associated with the ...
Huang, Fa Peng, Zhang, Xinmin
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Development of Clinical Reasoning and History-Taking Remediation Training

Journal of Medical Education and Family Medicine
Objective: Clinical reasoning and history skills are essential for health care professionals. The design of "remediation" training to compensate for "learning gaps", which may occur for various reasons in educational programs, is recommended.
Mukadder İnci Başer Kolcu, Sebahat Ulusan, Giray Kolcu   +2 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Prediction of food allergens sensitization based on history taking technique in young children [PDF]

, 2020
Jeongmin Lee, Kyunguk Jeong, Sooyoung Lee   +2 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Importance of physician history taking in complementing patient-reported interstitial lung disease questionnaire [PDF]

, 2022
Tal Moshe Perluk, Inbal Friedman Regev, Ophir Freund, Eyal Kleinhendler, Tzlil Hershko, Sharona Ben-Ami, Amir Bar‐Shai, Avraham Unterman   +7 more
openalex   +1 more source

Producers versus Profiteers: The Politics of Class in Newfoundland during the First World War [PDF]

, 2011
During the First World War a widespread public impression that merchants were taking advantage of the conflict to extract excessive profits became a major issue in Newfoundland politics, and a cause of widespread public discontent.
O'Brien, Mike
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Using Generative AI to Simulate Patient History-Taking in a Problem-Based Learning Tutorial: A Mixed-Methods Study [PDF]

Allison Mool, Jacob Schmid, Thomas Johnston, Kodi J. Smith McCoy, Zachary Patterson, Hannah Feldt, William Thomas, Emma Fenner, Kevin Lu, Raya A. Gandhi, Adam Western, Brendan Seabold, Daniel Vollmer, Roshan Nallaveettil, Anthony Fanelli, Logan Schmillen, Shelley Tischkau, Anna T. Cianciolo, Pinckney Benedict, Richard Selinfreund   +19 more
openalex   +3 more sources