Results 71 to 80 of about 430,069 (325)

The Randomized First-Hitting Problem of Continuously Time-Changed Brownian Motion

open access: yesMathematics, 2018
Let X ( t ) be a continuously time-changed Brownian motion starting from a random position η , S ( t ) a given continuous, increasing boundary, with S ( 0 ) ≥ 0 , P ( η ≥ S ( 0 ) ) = 1 , and F an assigned ...
Mario Abundo
doaj   +1 more source

Hitting densities for spectrally positive stable processes

open access: yes, 2010
A multiplicative identity in law connecting the hitting times of completely asymmetric $\alpha-$stable L\'evy processes in duality is established. In the spectrally positive case, this identity allows with an elementary argument to compute fractional ...
Simon, Thomas
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Approximating the Randomized Hitting Time Distribution of a Non-stationary Gamma Process [PDF]

open access: yes
The non-stationary gamma process is a non-decreasing stochastic process with independent increments. By this monotonic behavior this stochastic process serves as a natural candidate for modelling time-dependent phenomena such as degradation. In condition-
Frenk, J.B.G., Nicolai, R.P.
core   +4 more sources

Use of ammunition with programmable blasting time in air-defense complex

open access: yesНаука і техніка Повітряних Сил Збройних Сил України, 2020
The rapid spread and wide availability of unmanned aerial vehicle technologies creates a new type of airborne threat - massive and cheap strike and reconnaissance drones.
В.В. Воїнов
doaj   +1 more source

Maximizing the probability of attaining a target prior to extinction

open access: yes, 2009
We present a dynamic programming-based solution to the problem of maximizing the probability of attaining a target set before hitting a cemetery set for a discrete-time Markov control process.
Abate   +37 more
core   +4 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Running-Time Analysis of Brain Storm Optimization Based on Average Gain Model

open access: yesBiomimetics
The brain storm optimization (BSO) algorithm has received increased attention in the field of evolutionary computation. While BSO has been applied in numerous industrial scenarios due to its effectiveness and accessibility, there are few theoretical ...
Guizhen Mai   +6 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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