Results 81 to 90 of about 141,192 (322)

Genetic diversity and drug resistance of HIV-1 among infected pregnant women newly diagnosed in Luanda, Angola.

PLoS ONE, 2019
Monitoring genetic diversity and drug resistance mutations (DRMs) is critical for understanding HIV epidemiology. Here, we report HIV-1 genetic diversity and DRMs in blood samples from 42 HIV-positive pregnant women naive to antiretroviral therapy (ART),
Cruz S Sebastião, Zoraima Neto, Carlos S de Jesus, Marinela Mirandela, Domingos Jandondo, José C Couto-Fernandez, Amilcar Tanuri, Joana Morais, Miguel Brito   +8 more
doaj   +1 more source

Genetic attributes of cerebrospinal fluid-derived HIV-1 env [PDF]

, 2017
HIV-1 often invades the CNS during primary infection, eventually resulting in neurological disorders in up to 50% of untreated patients. The CNS is a distinct viral reservoir, differing from peripheral tissues in immunological surveillance, target cell ...
Ellis, Ronald J., Good, Benjamin M., Grant, Igor, Günthard, Huldrych F., Letendre, Scott, Liu, Yang, Marcotte, Thomas D., McCutchan, J. Allen, Pillai, Satish K., Pond, Sergei L. Kosakovsky, Richman, Douglas D., Smith, Davey M., Strain, Matthew C., Wong, Joseph K.   +13 more
core  

A Surface‐engineered Microfluidic Device for Antibody‐Mediated Negative Selection of High‐Quality Sperm for Assisted Reproduction

Advanced Functional Materials, EarlyView.
This study reports a microfluidic device with a functionalized surface utilizing a polyoxazoline coating and covalently immobilized gold nanoparticles and anti‐phosphatidylserine antibody. The device efficiently eliminates pre‐apoptotic and apoptotic spermatozoa and yields sperm with substantially improved quality and low DNA damage, offering a simple ...
Soraya Rasi Ghaemi, David J. Sharkey, Nicole O. McPherson, Markos Negash Alemie, Krasimir Vasilev, Sarah A. Robertson   +5 more
wiley   +1 more source

Molecular and genetic characteristics of Epstein-Barr virus isolates in adult patients with HIV infection in Nizhny Novgorod region

Инфекция и иммунитет
Introduction. According to foreing studies, the Epstein–Barr virus (EBV) isolates from individuals infected with the human immunodeficiency virus (HIV) are characterized by specific molecular genetic features compared to immunocompetent individuals.
Mariia I. Popkova, E. N. Filatova, S. V. Minaeva, N. A. Sakharnov, O. V. Utkin   +4 more
doaj   +1 more source

Human Immunodeficiency Virus-1 Diversity in the Moscow Region, Russia: Phylodynamics of the Most Common Subtypes

Frontiers in Microbiology, 2019
This study analyzes the HIV-1 subtype diversity and its phylodynamics in Moscow region, which is the most densely populated area of Russia characterized by high rates of internal and external migration.
Aleksey Lebedev, Natalya Lebedeva, Fedor Moskaleychik, Alexander Pronin, Elena Kazennova, Marina Bobkova   +5 more
doaj   +1 more source

Cerebrospinal fluid viral load and intrathecal immune activation in individuals infected with different HIV-1 genetic subtypes. [PDF]

PLoS ONE, 2008
HIV-1 exhibits a high degree of genetic diversity and is presently divided into 3 distinct HIV-1 genetic groups designated major (M), non-M/non-O (N) and outlier (O).
Sahra Abdulle, Lars Hagberg, Bo Svennerholm, Dietmar Fuchs, Magnus Gisslén   +4 more
doaj   +1 more source

Molecular epidemiology of Mycobacterium africanum in Ghana [PDF]

, 2016
BACKGROUND: Mycobacterium africanum comprises two phylogenetic lineages within the M. tuberculosis complex (MTBC) and is an important cause of human tuberculosis (TB) in West Africa. The reasons for this geographic restriction of M.
Ahorlu, Collins, Asante-Poku, Adwoa, Baddoo, Akosua, Bonsu, Frank, Borrell, Sonia, Forson, Audrey, Gagneux, Sebastien, Hattendorf, Jan, Koram, Kwadwo A., Laryea, Clement, Osei-Wusu, Stephen, Otchere, Isaac Darko, Sarpong, Esther, Yeboah-Manu, Dorothy   +13 more
core   +2 more sources

Nanodiamond Quantum Sensors for Probing Free Radical Biology

Advanced Functional Materials, EarlyView.
Free radicals play key roles in cellular signaling and disease but remain difficult to measure in living systems. Nanodiamonds (NDs) with nitrogen‐vacancy (NV) centers enable quantum sensing of local magnetic noise via T₁ relaxometry, providing nondestructive radical detection in living cells.
Qi Lu, Yingke Wu, Tanja Weil
wiley   +1 more source

Pathogenesis of HIV-1 and Mycobacterium tuberculosis co-infection [PDF]

, 2018
Co-infection with Mycobacterium tuberculosis is the leading cause of death in individuals infected with HIV-1. It has long been known that HIV-1 infection alters the course of M.
Bell, LCK, Noursadeghi, M
core  

Emerging PCR-based techniques to study HIV-1 reservoir persistence [PDF]

, 2020
While current antiretroviral therapies are able to halt HIV-1 progression, they are not curative, as an interruption of treatment usually leads to viral rebound.
Cole, Basiel, Lambrechts, Laurens, Rutsaert, Sofie, Trypsteen, Wim, Vandekerckhove, Linos   +4 more
core   +2 more sources