Results 141 to 150 of about 726,640 (329)

Spatiotemporal dynamics of HIV-1 transmission networks in a major migration hub: integrated phylogenetic and molecular evidence

Frontiers in Microbiology
ObjectiveHuman Immunodeficiency Virus type 1 (HIV-1) cross-regional transmission poses a critical challenge in China, particularly in high-mobility metropolitan centers.
Min Zhu, Min Zhu, Junfang Chen, Zhou Sun, Ke Xu, Ke Xu, Xingliang Zhang, Sisheng Wu, Ling Ye, Ling Ye, Xiaojuan Xu, Wenjie Luo   +11 more
doaj   +1 more source

Dental care associated with an outbreak of HIV infection among dialysis patients [PDF]

, 1997
Leonelo E. Bautista, Myriam Oróstegui
openalex   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Prevalence of HIV infection among sex workers and features of their risky behavior

, 2020
Е. И. Сисин, А. А. Голубкова, А. В. Алимов, V.I. Evseeva, N. D. Koneva, A. G. Gusev, E. V. Lelenkova, M. V. Piterskiy, A. S. Chebin   +8 more
openalex   +1 more source

Membralin Assembles a MAN1B1–VCP Complex to Target Foreign Glycoproteins from the Endoplasmic Reticulum to Lysosomes for Degradation

Advanced Science, EarlyView.
This study identifies Membralin as an ER‐phagy receptor that recruits MAN1B1 and VCP to form a selective ERLAD complex. By sensing dense N‐glycan clusters on viral fusion glycoproteins, this ubiquitin‐independent pathway directs SARS‐CoV‐2 spike, Ebola GP, influenza HA, and HIV‐1 Env to lysosomal degradation, thereby limiting viral infectivity ...
Jing Zhang, Xiaoran Lu, Sunan Li, Tao Wang, Iqbal Ahmad, Yong‐Hui Zheng   +5 more
wiley   +1 more source

Specific antibody‐dependent cellular cytotoxicity responses associated with slow progression of HIV infection

, 2012
Leia Wren, Amy W. Chung, Gamze Isitman, Anthony D. Kelleher, Matthew S. Parsons, Janaki Amin, David A. Cooper, Ivan Stratov, Marjon Navis, Stephen J. Kent   +9 more
openalex   +2 more sources

Disrupting Lipid Raft Microdomains to Block Polyploid Giant Cancer Cell Budding and Enhance Radiotherapy Response

Advanced Science, EarlyView.
Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng, Haoran Sun, Jin Cheng, Ruyi Zhao, Jianzhu Xie, Yanwei Song, Yucui Zhao, Chenwei Lin, Binjie Hu, Yanping Gong, Jun Lin, Sijia He, Yuntao Luo, Minghui Zhao, Yiwei Wang, Ming Jiao, Yuqin Yang, Jikun Li, Shujie Xia, Chuanyuan Li, Qian Huang   +20 more
wiley   +1 more source

Legal Barriers to Adolescent Participation in Research About HIV and Other Sexually Transmitted Infections

, 2015
Quianta Moore, Mary E. Paul, Amy L. McGuire, Mary A. Majumder   +3 more
openalex   +1 more source

Uncircumcised Men at Higher Risk of HIV Infection [PDF]

, 1994
Gina Pugliese
openalex   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source