Results 141 to 150 of about 1,054,313 (264)

Fouling‐Free Inertial Microfluidic Cell Clarification for Lentivirus Manufacturing

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Lentiviral vectors (LVVs) are widely used as gene‐delivery vehicles in cell and gene therapy, enabling stable integration of transgenes into target cells. However, efficient clarification of LVV harvest remains a major bottleneck in large‐scale manufacturing, as conventional depth filtration often results in significant product loss.
Dohyun Park   +5 more
wiley   +1 more source

Primary HIV [PDF]

open access: yesSexually Transmitted Infections, 2006
J, Fox, J, Weber, S, Fidler
openaire   +2 more sources

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

open access: yesBiological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke   +2 more
wiley   +1 more source

HIV Screening [PDF]

open access: yesBritish Journal of Psychiatry, 1989
openaire   +2 more sources

Humans are not unique: difficult birth is common in placental mammals

open access: yesBiological Reviews, EarlyView.
ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley   +1 more source

Stem-like CD8+ T cells preserve HBV-specific responses in HBV/HIV co-infection. [PDF]

open access: yesGut
Preechanukul A   +20 more
europepmc   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

open access: yesBiological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad   +5 more
wiley   +1 more source

Migration and its impact on universal HIV testing and treatment in the HPTN 071 (PopART) study communities. [PDF]

open access: yesPLOS Glob Public Health
Macleod D   +18 more
europepmc   +1 more source

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