Results 191 to 200 of about 1,322,023 (308)

Ferritin as a Nanoparticle Scaffold for Plant‐Produced Next‐Generation Subunit Vaccines

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Protein nanoparticles offer an innovative approach to next‐generation subunit vaccine development by displaying antigenic sequences on the nanoparticle surface. Compared to traditional subunit vaccines, protein nanoparticle vaccines often show improved interaction with the immune system due to their particulate size and repetitive epitope ...
Jordan T. VanderBurgt, Richard Strasser, Christopher P. Garnham, Rima Menassa   +3 more
wiley   +1 more source

Predictors of HIV reservoir size and decay dynamics in early-treated paediatric infection: a prospective, multicentre longitudinal cohort study. [PDF]

EBioMedicine
Reddy K, Domínguez-Rodríguez S, Molechan C, Cotton M, Otwombe K, Lain MG, Nhampossa T, Maiga AI, Barnabas S, Vaz P, Violari A, Fernández-Luis S, Behuhuma NO, Sylla M, Liberty A, Smit T, Ording-Jespersen G, Ismael N, Giaquinto C, Rossi P, Kuhn L, Palma P, Cotugno N, Spyer MJ, Magán AB, Oletto A, Dobbels E, Rojo P, Ndung'u T, Tagarro A, EPIICAL Consortium.   +30 more
europepmc   +1 more source

Isolating T‐Cell Potent Lentiviral Vector Subpopulations through Rational Design of Nanofiber Anion‐Exchange Adsorbents

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Generation of CAR‐T cell therapies relies predominantly on lentiviral vectors (LVs). As in vivo CAR‐T trials progress, demand for larger quantities of higher‐potency LV is expected. However, primary capture by anion‐exchange chromatography (AIEX) remains a major manufacturing bottleneck from use of adsorbents not tailored to LVs, leading to ...
George Pamenter, Gyorgy Ovari, Anurag Kulkarni, Thomas Williams‐Fegredo, Carol Knevelman, Kyriacos Mitrophanous, Lee Davies, Farzad Foroutan, Matthew Townsend, Stephen Goldrick, Daniel G. Bracewell   +10 more
wiley   +1 more source

Screening for HIV [PDF]

British Journal of Psychiatry, 1988
openaire   +2 more sources

Adverse Birth Outcomes Associated With SARS-CoV-2 Infection Among Pregnant Women With and Without HIV: A Longitudinal Cohort Study. [PDF]

J Acquir Immune Defic Syndr
Ahmed El-Imam I, Koudjra AR, Nampota-Nkomba N, Mkandawire F, Nyirenda O, Masonga R, Cairo C, Gladstone M, Laufer MK, Buchwald AG.   +9 more
europepmc   +1 more source

GlycoMAC: A Multiscale Metabolic‐Glycosylation Framework for Predicting Glycosylation Across Conditions in Mammalian Cell Cultures

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Antibody productivity and glycosylation quality in CHO cell cultures emerge from a dynamically evolving metabolic environment, yet existing models often work in isolation or at a single scale. Here, we present a multiscale mechanistic framework linking molecular, cellular, and macroscopic scales to predict how inputs shape bioprocess ...
Yuming Zeng, Sarah W. Harcum, Jinxiang Pei, Wei Xie   +3 more
wiley   +1 more source

Results of integrating recency testing into routine index testing services in Lusaka, Zambia: A mixed effects regression analysis. [PDF]

PLoS One
Pry JM, Iyer SS, Mwila C, Frimpong C, Moono M, Mulabe M, Nanyangwe M, Kapesa H, Phiri L, Maritim P, Arons MM, Aholou TM, Bolton Moore C, Savory-van Huis T, Herce ME.   +14 more
europepmc   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Impact of violence on HIV outcomes among female sex workers: A global systematic review and meta-analysis. [PDF]

PLoS Med
Dawe J, Mazhar KA, Khan SA, Njiro BJ, Bendaud V, Sabin K, Ambia J, Trickey A, Barrass L, Asgharzadeh A, Stone J, Artenie A, Vickerman P.   +12 more
europepmc   +1 more source