Results 191 to 200 of about 1,054,313 (264)

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

5' leader defects drive persistent HIV-1 viremia on long-term ART. [PDF]

Nat Commun
Box JR, Camilo-Contreras A, Dragoni F, Yue FY, Matveev V, Foley J, Zhang J, Mok YW, DeSousa M, Lai J, Mulcare Z, Bakewell Z, Poulin S, Chano F, Fortin C, Tremblay C, Blankson JN, Krishnan S, Weld ED, Basseth C, Hamill MM, Hoffmann CJ, Scully EP, Jones JL, Cox AL, El Atrouni W, Sha B, Siliciano JD, Siliciano RF, Reinhard R, Gunst JD, Ostrowski M, Maldarelli F, Kovacs C, Simonetti FR.   +34 more
europepmc   +1 more source

Lithium Diisopropylamide‐Mediated Ring‐Opening of Tetrahydrofuran in the Synthesis of Polyhydroxylated Indolizidines

European Journal of Organic Chemistry, EarlyView.
Chiral tri‐ and pentahydroxy spirocyclopentane‐indolizidines were synthesized using lithium diisopropylamide “LDA” promoted diallylation and tetrahydrofuran “THF” ring‐opening in a one‐pot procedure as a key step. The sequence leading to the targeted hydroxy‐spiroindolizidines was achieved by cis‐dihydroxylation followed by reduction of the enamine and
Paula Fraňová, Peter Šafář, Marchalín Štefan, Petra Pažitná, Ivana Žídeková, Ján Moncol, Adam Daïch   +6 more
wiley   +1 more source

U = U for all: Advancing equity in HIV prevention. [PDF]

PLoS Med
Torres TS, Luz PM.
europepmc   +1 more source

Electrochemical Three‐Component Synthesis of Heteroaryl Sulfonates

European Journal of Organic Chemistry, EarlyView.
An electrochemical, metal‐free three‐component strategy for direct C(sp2)─H sulfonation of electron‐rich heteroarenes using SO2 and alcohols is described. Utilizing inexpensive graphite electrodes and practical SO2 stock solutions under mild conditions, this method provides straightforward access to heteroaryl sulfonates from simple building blocks ...
Po‐Chung Chien, Harald Kelm, Georg Manolikakes   +2 more
wiley   +1 more source

<i>' … they just take one pill, so it is easy to use, more convenient … '</i>: South African health care provider perspectives on a Dual Prevention Pill. [PDF]

SAHARA J
Mathur S, Tenza S, Begg L, Mampuru L, Bruce IV, Moji M, Ndlovu N, Reddy K, Palanee-Phillips T, Friedland BA.   +9 more
europepmc   +1 more source

Development of Pentaplex Reverse Transcription Droplet Digital PCR Assay for Simultaneous Detection and Absolute Quantification of HIV‐1, HIV‐2, HCV, and HBV With Internal Control

ELECTROPHORESIS, EarlyView.
Development of Pentaplex reverse transcription droplet digital PCR assay for simultaneous detection and absolute quantification of HIV‐1, HIV‐2, HCV, and HBV with internal control. The channel‐resolved multiplex strategy enables high sensitivity, robust quantification, and scalable digital PCR workflows across platforms.
Soo Yeon Lim, Un Na Koh, Ah Leum Kim, Yebin Kim, Ga Eun Kim, Si‐Keun Lim   +5 more
wiley   +1 more source

Analysis of Viral Blips Through Week 192 of the DRIVE-FORWARD and DRIVE-AHEAD Phase 3 Studies of Doravirine-Based Regimens in Adults Living With Previously Untreated HIV-1. [PDF]

Open Forum Infect Dis
Molina JM, Orkin C, Paredes R, Xu ZJ, Su FH, Asante-Appiah E, Plank RM, Lahoulou R.   +7 more
europepmc   +1 more source

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

Electron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary, Harsh Sable, Sonu Sonu, Lakshita Phor, Reddicherla Umapathi, Pradeep Bhadola   +5 more
wiley   +1 more source

Incidence of HIV and HCV Among People Who Inject Drugs in Montreal, Canada: Data From the HEPCO Longitudinal Cohort Study, 2011-2025. [PDF]

J Viral Hepat
Kleiner BB, Meconnen M, Azar M, Minoyan N, Zang G, Artenie A, Martel-Laferrière V, Jutras-Aswad D, Bruneau J, Larney S.   +9 more
europepmc   +1 more source