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Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease.
Annual Review of Immunology, 1999In addition to CD4, the human immunodeficiency virus (HIV) requires a coreceptor for entry into target cells. The chemokine receptors CXCR4 and CCR5, members of the G protein-coupled receptor superfamily, have been identified as the principal coreceptors
E. Berger, P. Murphy, J. Farber
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Consider HIV--testing for HIV and HIV indicator diseases.
Australian family physician, 2014Since the advent of highly active antiretroviral therapy (HAART), human immunodeficiency virus (HIV) can be considered a treatable condition. In Australia in 2010, 40% of people had their HIV diagnosed late, where late is defined as CD4
Bell, C., Waddell, R., Chynoweth, N.
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On the road to an HIV vaccine?
Nature Reviews Immunology, 2015A new construct termed eCD4-Ig neutralizes all tested HIV isolates and protects macaques from multiple SHIV challenges.
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CC CKR5: A RANTES, MIP-1α, MIP-1ॆ Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1
Science, 1996Human immunodeficiency virus-type 1 (HIV-1) entry requires fusion cofactors on the CD4+ target cell. Fusin, a heterotrimeric GTP-binding protein (G protein)-coupled receptor, serves as a cofactor for T cell line-tropic isolates.
G. Alkhatib+6 more
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Identification of a major co-receptor for primary isolates of HIV-1
Nature, 1996H. Deng+14 more
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Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
Nature, 1995D. Ho+5 more
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Biomedical and environmental sciences : BES, 2014
Yi Ming Shao, Li Ying Ma, Qian Qian Yin
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Yi Ming Shao, Li Ying Ma, Qian Qian Yin
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