Results 301 to 310 of about 314,387 (344)

Understanding HIV-1 Drug Resistance

Therapeutic Drug Monitoring, 2004
Infection with drug-resistant HIV-1 may result from the acquisition of mutant strains or from their selection within the individual; either can compromise the efficacy of antiretroviral therapy (ART). Drug-resistance testing is recommended to assist in the choice of ART.
Lisa M, Frenkel, Nicole H, Tobin
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Testing for HIV-1 drug resistance

Molecular Diagnosis, 2001
Viral resistance to antiretroviral agents may limit the efficacy of current treatment regimens for HIV-1 infection. The mutational patterns underlying resistance to each antiretroviral agent are often quite diverse, and cross-resistance patterns in each of the currently available classes are complex.
G J, Hanna, A M, Caliendo
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HIV Drug Resistance Testing

2010
HIV genotypic resistance testing has become a routine test informing the management of HIV-positive patients. This chapter describes the background of this testing and provides a protocol for undertaking the assay by a home-brew method. Methods for interpretation of the data are also outlined.
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Adherence and HIV Drug Resistance

HIV Clinical Trials, 2004
(2004). Adherence and HIV Drug Resistance. HIV Clinical Trials: Vol. 5, No. 2, pp. 112-115.
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Global HIV drug resistance surveillance

Scandinavian Journal of Infectious Diseases, 2003
The transmission of drug-resistant strains of human immunodeficiency virus (HIV) is of increasing concern in countries where antiretroviral therapy is widely used and does not spare countries where highly effective antiretroviral therapy has been recently introduced.
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Drug resistant tuberculosis and HIV

Nursing Standard, 1990
High frequencies of drug resistant tuberculosis in people who are HIV positive are reported from America.
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Reversibility of HIV Drug Resistance

Science, 2000
Using a mathematical model, Blower et al . ([1][1]) predicted the impact of antiretroviral therapy (ART) on future trends in the sexual spread of human immunodeficiency virus (HIV). The model employed Latin hypercube sampling to allow for the high degree of uncertainty in the estimation of ...
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Structural Mechanisms of HIV Drug Resistance

Annual Review of Pharmacology and Toxicology, 1996
Antiviral therapy for AIDS has focused on the discovery and design of inhibitors for two main enzyme targets of the human immunodeficiency virus type 1 (HIV)--reverse transcriptase (RT) and protease (PR). Despite several classes of promising new anti-HIV agents, the clinical emergence of drug-resistant variants of HIV has severely limited the long-term
J W, Erickson, S K, Burt
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Transmission of HIV-1 drug resistance

Journal of Clinical Virology, 2004
The use of highly-active anti-retroviral therapy (HAART) for treating HIV infections is increasing. Recent studies have demonstrated that HAART is improving both the length and quality of life in HIV-infected patients. Resistant strains of HIV arise when drug adherence is poor.
Julian W, Tang, Deenan, Pillay
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HIV-1 Drug Resistance

2005
These issues also impact the question of postexposure prophylaxis in the occupational setting; resistance considerations in this context should not be ignored. One special subject, widely practiced at this time, is the use of drugs to prevent mother-to-infant transmission of HIV-1.
Mark A. Wainberg, Bluma G. Brenner
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