Results 181 to 190 of about 7,403,959 (300)

Cost-Effectiveness of the I'm Ready HIV Self-Testing Programme Among High-Risk Populations in Canada. [PDF]

J Int AIDS Soc
Masucci L, Jalal H, Rourke SB, McBain K, Xi M, Zhang W, Nguyen HV, Wong WWL, Gill MJ, Zwerling A, Thavorn K.   +10 more
europepmc   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

HIV self-testing and its associated factors among nursing and medical university students: A cross-sectional study in EasternUganda. [PDF]

BMC Infect Dis
Nambi W, Nabirye RC, Olowo S, Nabawanuka B, Kakyo TA, Turyasiima M, Nakato G, Aleni M, Lume I, Nabachenje P, Epuitai J.   +10 more
europepmc   +1 more source

HIV testing trends in the United States, 2000-2011 [PDF]

The purpose of this report is to examine HIV testing trends from 2000 to 2011 in the United States in order to consider the impact of CDC's Revised Recommendations for HIV Testing of Adults, Adolescents, and Pregnant Women in Health-Care Settings and ...
National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (U.S.) Division of HIV/AIDS Prevention.
core  

Peptide‐based antibacterial nanoplatforms: Design principles, stimuli‐regulated behaviors, and applications

Responsive Materials, EarlyView.
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan, Chenlong Zhou, Shuaikang Yang, Zhenduo Chen, Guanghui Zhao, Qi Tang, Haoyu Yan, Feng Li, Xi Ma   +8 more
wiley   +1 more source

Acceptability, Usability, and Clinical Appropriateness of an AI-Powered Tool for Linkage to HIV Services After HIV Self-Testing in South Africa: Mixed Methods Evaluation. [PDF]

J Med Internet Res
Mahlalela NB, Maboa O, Govathson C, Rossouw L, Long L, Greener R, Morris S, Cooper S, Frade S, Pascoe S, Chetty-Makkan C.   +10 more
europepmc   +1 more source

The Mitigating Role of Managerial Ability in ESG Decoupling

Sustainable Development, EarlyView.
ABSTRACT Does managerial competence widen or bridge the gap between environmental, social, and governance (ESG) disclosures and actual performance? This paper explores the relationship between CEO ability and corporate decoupling regarding sustainability issues.
Isabel‐María García‐Sánchez, Rizwan Ali, Alejandra García‐Sánchez, Ramiz ur Rehman   +3 more
wiley   +1 more source

Stoichiometric Binding of Cyclophilin‐A to The HIV‐1 Capsid Modulates Its Mechanoelastic Properties

Small, EarlyView.
The HIV‐1 capsid is a protein nanocapsule that must balance rigidity and flexibility to enter the cell nucleus. Atomic force microscopy simulations reveal that binding of the host protein Cyclophilin A tunes this mechanical response: partial coverage preserves deformability, while excessive binding induces brittleness and failure.
Juan S. Rey, Alexander J. Bryer, Juan R. Perilla   +2 more
wiley   +1 more source

Trends in HIV self-testing uptake in Africa: A modeling study of population-based surveys and HIV testing program data. [PDF]

PLoS Med
Aratrika A, Doyle CM, Johnson CC, Edun O, Mbope B, Adoko A, Tlhomola M, Yansouni CP, Choko AT, Imai-Eaton JW, Maheu-Giroux M.   +10 more
europepmc   +1 more source

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

Smart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin, Rui Peng, Guangshuai Zhang, Si Yan, Jin Xiao, Zishu Liu, Ziyu Tan, Qingqing Xie, Shangjie Li, Wei Luo, Xiaohe Xiao   +10 more
wiley   +1 more source