Results 61 to 70 of about 31,626 (234)

The Expanding Landscape of Microbiota Medicine: Indications, Therapeutic Modalities, and the Path Towards Integrative Microbiome‐Targeting Healthcare

Microbiota Medicine Research, EarlyView.
ABSTRACT The growing recognition of the microbiome's role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai, Yisha Lin, Renyou Gan, Xiaotao Shen, Shin Young Park, Sunjae Lee, Qi Su   +6 more
wiley   +1 more source

Seroprevalence of varicella zoster antibodies among children with malnutrition, malignancies and HIV infection [PDF]

, 2008
Objective: To determine the seroprevalence of varicella zoster in paediatric patients at a high risk of developing complications. Design: A cross-sectional study. Setting: Paediatric general wards at Kenyatta National Hospital.
Admani, Bashir, Macharia, William, Were, F.   +2 more
core   +3 more sources

Considerations for the clinical use of teplizumab in stage 2 Type 1 diabetes: A Consensus Statement from the British Society of Paediatric Endocrinology and Diabetes (BSPED) and the Association of British Clinical Diabetologists (ABCD)

Diabetic Medicine, EarlyView.
Abstract Introduction In 2025, the Medicines and Healthcare products Regulatory Agency (MHRA) approved the use of teplizumab (a monoclonal anti‐CD3 antibody) to delay progression from Stage 2 to Stage 3 Type 1 diabetes in the UK. Methods To address the need for clear guidance on managing patients eligible for teplizumab therapy, the British Society of ...
Renuka P. Dias, M. Loredana Marcovecchio, Ruben H. Willemsen, Fiona Campbell, Ahmad Ashour, Philip Newland‐Jones, Jennifer Cooper, Parth Narendran, Neil P. Wright   +8 more
wiley   +1 more source

Seroprevalence of HIV, HBV, HCV and Syphilis in Blood Donors in Saurashtra Region of Gujarat: Declining Trends Over a Period of 3½ Years [PDF]

, 2012
Background: Transfusion of blood and blood products is a life saving intervention and benefits innumerous patients worldwide. At the same time it could be an ominous mode of infection transmission to recipients.
Agravat, AH, Dhruva, GA, Pujara, KM
core   +1 more source

Field evaluation of two point-of-care tests for syphilis among men who have sex with men, Verona, Italy [PDF]

, 2017
Objectives: The incidence of HIV and syphilis among men who have sex with men (MSM) in Europe has recently increased. Rapid point-of-care tests (POCTs) for syphilis can improve access to screening.
Ballard, Ronald, Blondeel, Karel, Cordioli, Maddalena, Cornaglia, Giuseppe, Del Bravo, Paola, Gios, Lorenzo, Kiarie, James, Mirandola, Massimo, Peeling, Rosanna W, Toskin, Igor, Zorzi, Antonella   +10 more
core   +2 more sources

Bringing Gene Therapy Into Real World Clinical Practice

Haemophilia, EarlyView.
ABSTRACT Introduction Adeno‐associated virus (AAV)‐based gene therapy for haemophilia has shifted therapeutic paradigms by enabling hepatic gene transfer, restoring endogenous clotting factor expression, and reducing reliance on conventional prophylactic treatments. Two products, valoctocogene roxaparvovec (haemophilia A) and etranacogene dezaparvovec (
Wolfgang Miesbach, Pratima Chowdary, Margareth C. Ozelo   +2 more
wiley   +1 more source

Measles immunity among pregnant women aged 15–44 years in Namibia, 2008 and 2010

International Journal of Infectious Diseases, 2016
Background: Namibia experienced a large measles outbreak starting in 2009, with 38% of reported cases in adults, including women of reproductive age. Population immunity was assessed among pregnant women to determine whether immunization activities were ...
Cristina V. Cardemil, Anna Jonas, Anita Beukes, Raydel Anderson, Paul A. Rota, Bettina Bankamp, Howard E. Gary Jr, Souleymane Sawadogo, Sadhna V. Patel, Sikota Zeko, Clementine Muroua, Esegiel Gaeb, Kathleen Wannemuehler, Sue Gerber, James L. Goodson   +14 more
doaj   +1 more source

High prevalence of antibodies to human herpesvirus 8 in relatives of patients with classic Kaposi's sarcoma from Sardinia [PDF]

, 1998
A survey for antibodies to a recombinant small viral capsid antigen (sVCA) of human herpesvirus type 8 (HHV‐8) was conducted in Sardinia, one of the world's highest incidence areas for classic Kaposi's sarcoma (KS). Prevalence of antibodies to HHV‐8 sVCA
Angeloni, Antonio, Cerimele, Decio, Cottoni, Francesca Maria Giovanna, Faggioni, Alberto, Heston, Lee, Lin, Su-Fang, Masala, Maria Vittoria, Miller, George, Rigsby, Michael, Sirianni, Maria Caterina, Sun, Ren, Uccini, Stefania   +11 more
core   +1 more source

Efficacy of dolutegravir/lamivudine in adults with HIV‐1 and isolated reactive hepatitis B core antibody: Insights from Phase 3/3b study results

HIV Medicine, EarlyView.
Abstract Objectives As two‐drug HIV‐1 antiretroviral therapy (ART) regimens become standard, data gaps remain concerning their safety and efficacy among people with isolated reactive hepatitis B core antibodies (anti‐HBc). Here, we assessed the safety and efficacy of dolutegravir/lamivudine (DTG/3TC) versus three‐ or four‐drug regimens (3DRs/4DRs ...
D. Fox, J. Slim, E. T. Overton, A. Doblado‐Maldonado, P. Jeffery, R. A. Grove, S. D. Advani, R. Borsi, C. M. Parry, M. Underwood, B. Jones   +10 more
wiley   +1 more source

Prevalence and Factors Associated with Hepatitis C Virus Infection among Myanmar Blood Donors [PDF]

, 2010
We studied the prevalence of hepatitis C virus infection among blood donors from 3 hospitals of Central Myanmar and 7 hospitals of Lower Myanmar in the Yangon area, and analyzed the factors associated with the infection.
Khin, May Oo, Koide, Norio, Myo-Khin,, Okada, Shigeru, San-San-Oo,, Shimono, Kunio   +5 more
core   +1 more source