Results 151 to 160 of about 273,812 (261)

A multiplex interactome of Ebola virus proteins reveals TM9SF2 as a cell‐surface attachment factor that promotes viral entry

iMetaOmics, EarlyView.
This study generates a comprehensive Ebola virus (EBOV)‐human protein–protein interactome, comprising 1728 core high‐confidence interactions. Further interactome analysis revealed the potential association of EBOV glycoprotein (GP) with the host factor TM9SF2. Subsequent mechanistic investigations confirmed that TM9SF2 functions as an attachment factor
Limin Shang, Shouwen Du, Yuchen Liu, Letian Li, Xi Wu, Yanzhi Yuan, Chaozhi Jin, Qingkun Mi, Yuhang Wang, Xiaoshuang Shi, Jiamin Wang, Guoqing Zhang, Yidan Ma, Weijin Huang, Jigang Wang, Jian Wang, Chang Li   +16 more
wiley   +1 more source

Prevalence and factors associated with uptake of repeat HIV testing among pregnant women in Blantyre, Malawi. [PDF]

BMC Public Health
Chikalipo MC, Kaula MP, Mwapasa V, Nyondo-Mipando AL.   +3 more
europepmc   +1 more source

Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI

iNew Medicine, EarlyView.
Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang, Yinbo Xu, Yiting Zhao, Liuyi Li, Zhengyi Cheng, Zhongqi Zhang, Yuhang Luo, Qiaoling Liu, Chen Gong, Shichun Shen   +9 more
wiley   +1 more source

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source

Barriers and facilitators to HIV testing among African and Caribbean heritage communities: a mixed methods study. [PDF]

Sex Transm Infect
Adeniyi T, Horwood J, Doran M, Piggott K, Namurach AM, Harryman L, Oldenbourg E, Kiflu M, Speare N, Griffin M, Wilson M, Febrache M, Allbless R, Dravie-John D, Copping J, De Vocht F, Walter S, Fox F.   +17 more
europepmc   +1 more source

Improving Linkage to the HCV Care Cascade in Nonspecialist Settings: Evaluation of the Performance and Triage Utility of the Elecsys HCV Duo Assay in Japan

Journal of Clinical Laboratory Analysis, EarlyView.
In nonspecialist departments, most anti‐HCV–positive individuals do not proceed to RNA testing. The Elecsys HCV Duo assay simultaneously detects anti‐HCV antibodies and core antigen from a single blood draw and preferentially identifies patients with clinically meaningful viral loads.
Hiroko Setoyama, Takehisa Watanabe, Shiho Miyase, Masakuni Tateyama, Motohiko Tanaka, Nobuhiro Minami, Masato Sasaki, Shunpei Hashigo, Kotaro Fukubayashi, Shotaro Ishii, Mutsuo Koga, Ryo Ichikawa, Hirofumi Iwashita, Yoshinari Sakai, Toshihiko Motohara, Kohei Tomita, Akinori Nakata, Yutaka Kai, Takeyasu Kounoe, Katsuki Haraoka, Takako Inoue, Takanori Suzuki, Kentaro Matsuura, Yasuhito Tanaka   +23 more
wiley   +1 more source

Geospatial and multilevel analysis of lifetime HIV testing uptake among high-risk adults in Mozambique: evidence from the 2022-2023 DHS. [PDF]

Int J Health Geogr
Yewodiaw TK, Endalew HL, Getnet M, Getahun AB, Mengstie TA, Enyew EF, Bitewa MD, Endale HT, Asefa T.   +8 more
europepmc   +1 more source

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

Determinants of HIV testing and oral PrEP uptake among youth at Malawi University of Business and Applied Sciences: A cross-sectional study employing the Health Belief Model. [PDF]

PLOS Glob Public Health
Mommertz JK, Kamanga M, Nyondo WM, Mapulanga P, Kumbani LC.   +4 more
europepmc   +1 more source

Mental health measures among adolescents in 12 low‐ and middle‐income countries: Measurement invariance and cross‐sectional analyses of Disrupting Harm survey data

JCPP Advances, EarlyView.
Abstract Background Nationally representative mental health data in adolescents from low‐ and middle‐income countries (LMICs) are scarce. This study aimed to examine mental health and wellbeing indicators amongst adolescents in 12 LMICs across Eastern and Southern Africa and Southeast Asia. Methods We conducted a secondary analysis of data involving 12,
Ariadna Albajara Sáenz, Sebastian Kurten, Jennifer Saxton, Daniel Kardefelt‐Winther, Tamsin Ford, Amy Orben, Simon R. White   +6 more
wiley   +1 more source