British Journal of Clinical Pharmacology, EarlyView.Long‐acting intramuscular cabotegravir/rilpivirine (LA CAB/RPV) is contraindicated with rifampicin because of the risk of markedly reduced antiretroviral exposure, although clinical pharmacokinetic data for this interaction are lacking. We describe a 49‐year‐old man with virologically suppressed HIV‐1 infection receiving LA CAB/RPV every 8 weeks who ...
Emilie M. Gieling +6 more
wiley +1 more source
Resident based disparities in HIV testing among the general population in Ethiopia: Evidence from the Ethiopian Demographic Health Survey. [PDF]
Public Health Pract (Oxf)Alemu SB +4 more
europepmc +1 more source
Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production
Biotechnology and Bioengineering, EarlyView.ABSTRACT Stable lentiviral vector producer cell lines represent a promising platform for scalable and cost‐efficient vector manufacturing, yet their productivity is often limited by intrinsic host‐cell constraints. In this study, we aimed to identify cellular factors restricting LVV production in stable doxycycline‐inducible GPRTG producer cell lines ...
Jona Röscheise +3 more
wiley +1 more source
Opt-in and opt-out strategies for HIV testing. [PDF]
Lancet Reg Health EurMiró E +5 more
europepmc +1 more source
Ferritin as a Nanoparticle Scaffold for Plant‐Produced Next‐Generation Subunit Vaccines
Biotechnology and Bioengineering, EarlyView.ABSTRACT Protein nanoparticles offer an innovative approach to next‐generation subunit vaccine development by displaying antigenic sequences on the nanoparticle surface. Compared to traditional subunit vaccines, protein nanoparticle vaccines often show improved interaction with the immune system due to their particulate size and repetitive epitope ...
Jordan T. VanderBurgt +3 more
wiley +1 more source
Opt-in and opt-out strategies for HIV testing-author's reply. [PDF]
Lancet Reg Health EurParczewski M.
europepmc +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Generation of CAR‐T cell therapies relies predominantly on lentiviral vectors (LVs). As in vivo CAR‐T trials progress, demand for larger quantities of higher‐potency LV is expected. However, primary capture by anion‐exchange chromatography (AIEX) remains a major manufacturing bottleneck from use of adsorbents not tailored to LVs, leading to ...
George Pamenter +10 more
wiley +1 more source
Qualitative Study of Healthcare Providers and Test Recipients on Progress and Implementation Gaps in HIV Testing Strategies - Five Regions, China, November 2023-July 2024. [PDF]
China CDC WklyShi L +8 more
europepmc +1 more source
Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality
BMEMat, EarlyView.Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim +9 more
wiley +1 more source
Implementation of Health Insurance Navigation for Racial/Ethnic Minority Men Who Have Sex With Men Presenting for Community-Based HIV Testing. [PDF]
J Acquir Immune Defic SyndrRoland KB +6 more
europepmc +1 more source