Results 41 to 50 of about 3,269,718 (260)

A costing analysis of B-GAP: index-linked HIV testing for children and adolescents in Zimbabwe

BMC Health Services Research, 2021
Background By testing children and adolescents of HIV positive caretakers, index-linked HIV testing, a targeted HIV testing strategy, has the ability to identify high risk children and adolescents earlier and more efficiently, compared to blanket testing.
Arthi Vasantharoopan, Hendramoorthy Maheswaran, Victoria Simms, Chido Dziva Chikwari, Tariro Chigwenah, Rudo Chikodzore, Khulamuzi Nyathi, Gertrude Ncube, Rashida A. Ferrand, Lorna Guinness   +9 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

An exploratory study into the factors that constrain or enable voluntary HIV testing among young adults in Cape Town, South Africa [PDF]

, 2008
Includes bibliographical references (leaves 73-81).Despite exceptionally high HIV prevalence rates, South Africa experiences prohibitively low levels of HIV testing.
Lane, Hannah
core   +1 more source

Addressing Psychosocial Syndemic Conditions to Improve HIV Testing among Men Who have Sex with Men in Chandigarh, India: Results from a Quasi-Experimental Implementation Research Study

Indian Journal of Public Health
To improve HIV testing uptake, we implemented a syndemic theory-based intervention targeting syndemic conditions such as depression, internalized homonegativity, and problematic alcohol use among men who have sex with men in Chandigarh (baseline n = 2046;
Venkatesan Chakrapani, Manmeet Kaur, Deepalatha Shetty, Gurjinder Kaur, Sandeep Mittal, Rajesh Kumar   +5 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

‘Cost, man. Good quality stuff can get pricey’, men’s choices regarding HIV services in South Africa

African Journal of Primary Health Care & Family Medicine
Background: Despite global declines in human immunodeficiency virus (HIV) infections, South African men remain disproportionately affected. Understanding men’s HIV service preferences is essential for designing effective interventions.
Patience Manjengwa, Clarence Yah, Alfred Musekiwa   +2 more
doaj   +1 more source

Peer interventions to improve HIV testing uptake among immigrants: A realist review [PDF]

Health Promotion Perspectives
Background: As a vulnerable group in HIV control programs, immigrants face various obstacles to HIV testing. Despite the effectiveness of peer interventions on health promotion in HIV testing, relatively little is known about how these interventions work.
Elham Ghasemi, Tahereh Bahrami, Reza Majdzadeh, Reza Negarandeh, Fatemeh Rajabi   +4 more
doaj   +1 more source

Private providers and HIV testing in Pune, India: challenges and opportunities.

, 2005
We explored HIV testing practices of private medical providers in an urban Indian setting in Pune, western India. 215 private practitioners (PPs) and 36 persons-in-charge of private laboratories were interviewed in separate surveys.
Porter, John, Deshpande, Sucheta, Rangan, Sheela, Datye, Vinita, Sheikh, Kabir, Kielmann, Karina   +5 more
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source