Results 61 to 70 of about 8,699 (152)

On nouniqueness of solutions of Hamilton-Jacobi-Bellman equations

, 2015
An example of a nonunique solution of the Cauchy problem of Hamilton-Jacobi-Bellman (HJB) equation with surprisingly regular Hamiltonian is introduced. The proposed Hamiltonian H(t,x,p) fulfills the local Lipschitz continuity with respect to the triple ...
Misztela, Arkadiusz
core   +1 more source

Breastmilk and medium‐chain triglyceride supplementation: Retrospective study on outcomes in biliary atresia infants after Kasai

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Does breastmilk with medium‐chain triglycerides (MCT) after Kasai support growth and improve surgical outcomes? Abstract Objective To relate post‐surgical feeding regimens to growth and surgical outcomes in children with biliary atresia (BA) after hepato‐portoenterostomy (Kasai).
Thora Wesenberg Helt, Ruben H. de Kleine, Lars Søndergaard Johansen, Tietie Dijkstra, Jan B. F. Hulscher, Henkjan J. Verkade, Vibeke Brix Christensen   +6 more
wiley   +1 more source

Increased expression of aromatase after focal cerebral ischemia: Relevance to neuroprotection and functional recovery

Neuroprotection, EarlyView.
Abstract Aim Aromatase is the key enzyme in the biosynthesis of 17β‐estradiol, the most potent estrogen, which has pleiotropic neuroprotective properties. Aromatase levels increase in the brain after stroke, and its gene variants increase susceptibility to stroke. This study aims to determine whether aromatase overexpression improves stroke outcome and
Lindsay Gallagher, Anna F. Dominiczak, Luis M. Garcia‐Segura, Nobuhiro Harada, J. B. Hutchison, James M. Mullin, Delyth Graham, Peter O'Shaughnessy, Hilary Victoria O. Carswell   +8 more
wiley   +1 more source

Adaptive Actor–Critic Optimal Tracking Control for a Class of High-Order Nonlinear Systems with Partially Unknown Dynamics

Actuators
Optimal tracking control for high-order partially unknown nonlinear systems poses significant challenges, particularly in deriving tractable solutions without requiring persistent excitation (PE) conditions or precise system models.
Dengguo Xu, Xinsuo Li, Fapeng Li, Jingbei Tian   +3 more
doaj   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said, Job R. Schippers, Leila Atmowihardjo, Yingxue Li, Mick S. van der Plas, Harm J. Bogaard, Lieuwe D. J. Bos, Ron A. A. Mathôt, Jurjan Aman, Eleonora L. Swart, Imke H. Bartelink   +10 more
wiley   +1 more source

Dental Factors Associated With Oropharyngeal Dysphagia in Institutionalised Older Adults: A Systematic Review

Gerodontology, EarlyView.
ABSTRACT Background Aging is associated with a decline in physiological functions. Dysphagia, a disorder among older adults, impairs feeding and is related to morphological and functional changes in the stomatognathic system, which worsen with age‐related physiological decline, particularly among institutionalised older adults.
Raquel Soncini de Morais, Juliana Balbinot Hilgert, Fernando Neves Hugo, Rafaela Soares Rech   +3 more
wiley   +1 more source

Model Ambiguity versus Model Misspecification in Dynamic Portfolio Choice

The Journal of Finance, EarlyView.
ABSTRACT We study aversion to model ambiguity and misspecification in dynamic portfolio choice. Risk‐averse investors (relative risk aversion γ>1$\gamma > 1$) fear return persistence, while risk‐tolerant investors (0<γ<1$0<\gamma <1$) fear mean reversion, when confronting model misspecification concerns of identically and independently distributed (IID)
PASCAL J. MAENHOUT, HAO XING, ANNE G. BALTER   +2 more
wiley   +1 more source

A Review of Tipping Points and Precaution using HJB equations

Dynamic Games and Applications, 2023
AbstractThis paper analyzes three models in environmental economics with the property that tipping can occur in the ecological part of the model: the pollution control model where tipping suddenly shifts up the damage, the fishery model where tipping suddenly lowers the carrying capacity, and the Ramsey growth model where tipping suddenly decreases the
openaire   +2 more sources

Reinforcement Learning for Jump‐Diffusions, With Financial Applications

Mathematical Finance, EarlyView.
ABSTRACT We study continuous‐time reinforcement learning (RL) for stochastic control in which system dynamics are governed by jump‐diffusion processes. We formulate an entropy‐regularized exploratory control problem with stochastic policies to capture the exploration–exploitation balance essential for RL.
Xuefeng Gao, Lingfei Li, Xun Yu Zhou
wiley   +1 more source

Nationwide pediatric prehospital blood product use after motor vehicle crashes 2020–2023

Transfusion, EarlyView.
Abstract Background Previous studies suggest that in children with hemorrhagic shock following injury, prehospital blood transfusion improves survival. Quantifying and understanding the current demand for blood transfusion will help us improve the use and availability of prehospital blood for pediatric patients.
Chandler A. Annesi, Christine Carico, Daniel T. Lammers, N. Clay Mann, Matthew J. Levy, Pawan Acharya, Jan O. Jansen, Jeffrey D. Kerby, Robert T. Russell, John B. Holcomb, Zain G. Hashmi   +10 more
wiley   +1 more source