Results 181 to 190 of about 730,257 (221)

MiR-518c-5p/miR-4524a-3p can mediate immune escape and chemotherapy resistance in triple-negative breast cancer and predict its outcome. [PDF]

Hereditas
Sun Y, An L, Kong L, Liu X, Zhang H, Liu J, Qian P.   +6 more
europepmc   +1 more source

The Origins of Allergy: An Outside‐In, Bioenergetic Hypothesis

Allergy, EarlyView.
ABSTRACT Allergic disease has risen too rapidly for inherited susceptibility to explain it, and the risk variants so far reported lie in the epithelial barrier and in type‐2 immunity. We propose a five‐layer model in which epithelial barrier and bioenergetic dysfunction may precede and promote type‐2 immune deviation rather than arise solely as its ...
Peter K. Smith, Nicholas P. West, Stanley Du Preez, Hugh A. Sampson, Peter W. Hellings, David Price, Liam O'Mahony, Carina Venter, Cezmi A. Akdis, Gil Yosipovitch   +9 more
wiley   +1 more source

The key pathways and genes related to oncolytic Newcastle disease virus-induced phenotypic changes in ovarian cancer cells. [PDF]

J Microbiol
Song W, Yuan Y, Cao F, Pan H, Liu Y.
europepmc   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

Andrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz, Wioletta Lech, Anna Figiel‐Dabrowska, Marta Kot, Magdalena Murzyn, Natalia Malawska, Barbara Pienkowska‐Grela, Zuzanna Sandowska‐Markiewicz, Iwona Ziolkowska‐Suchanek, Agnieszka Zimna, Tomasz Oldak, Natalia Rozwadowska, Anna Sarnowska   +12 more
wiley   +1 more source

Mesenchymal stromal cell therapy for systemic lupus erythematosus: mechanisms, clinical translation, and future directions. [PDF]

Stem Cell Res Ther
Ding S, Wu S, Cui Y, Zhou Y, Qiu S, Ye Z, Ma R, Wan YW, Ying Z.   +8 more
europepmc   +1 more source

Abdominal Normothermic Regional Perfusion Versus Normothermic Machine Perfusion of DCD Kidneys Aged 50 Years or Older: A Propensity Score Matched Analysis

Artificial Organs, EarlyView.
This study compares abdominal normothermic regional perfusion (aNRP) and normothermic machine perfusion (NMP) for kidney transplants from older donation after circulatory death (DCD) donors. Both techniques showed similar outcomes in delayed graft function, primary non‐function, acute rejection, and long‐term kidney function, suggesting they may ...
J. S. Slagter, E. F. van de Geijn, F. H. C. de Goeij, P. C. Groen, I. J. Schurink, I. P. J. Alwyn, R. J. Porte, V. A. L. Huurman, J. de Jonge, R. C. Minnee   +9 more
wiley   +1 more source

The impact of tislelizumab immunotherapy on multiple primary lung cancer presenting as ground-glass nodules: preliminary results analysis from a single-arm, phase II trial. [PDF]

Cancer Immunol Immunother
Wu J, Fu X, Gao Y, Qin S, Xiong J, Qu R, Cai Y.   +6 more
europepmc   +1 more source

The Anti‐Inflammatory Effect of Normothermic Machine Perfused Human Kidneys on Monocyte‐Derived Dendritic Cells

Artificial Organs, EarlyView.
The immunogenicity of donor kidneys on NMP can be studied using monocyte‐derived dendritic cells. Incubation with perfusate showed an anti‐inflammatory dendritic cell phenotype and function that suggests the release of an anti‐inflammatory factor or factors during NMP. ABSTRACT Background The immunomodulatory activity of normothermic machine perfusion (
Laura W. D. Knijff, Asel S. Arykbaeva, Sandra W. van der Kooij, Dorottya K. de Vries, Mieke F. van Essen, Ian P. J. Alwayn, Henri G. D. Leuvenink, Rutger J. Ploeg, Cees van Kooten   +8 more
wiley   +1 more source

[Clinical significance of antiphospholipid antibodies in Behcet disease with thrombosis]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Li Y, Wang H, Luo L, Li Y, Li C.
europepmc   +1 more source

Development of a Clinical and Biomarker‐Based Score to Predict Microscopic Colitis in Patients With Chronic Watery Diarrhoea

Alimentary Pharmacology &Therapeutics, EarlyView.
The MC‐fCAL score combines simple clinical variables and faecal calprotectin to predict microscopic colitis in patients with chronic watery diarrhoea. It showed promising diagnostic accuracy and may support future risk‐stratified diagnostic pathways by identifying patients with a low estimated probability or a strong suspicion of microscopic colitis ...
Laura Ruiz‐Campos, Yamile Zabana, Lissette Batista, Danila Guagnozzi, Ingrid Fajardo, Pablo Ruiz‐Ramírez, Carme Loras, Maria Esteve, Fernando Fernández‐Bañares   +8 more
wiley   +1 more source