Results 241 to 250 of about 93,215 (258)
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Arthritis & Rheumatism, 2004
OBJECTIVE A disease resembling the human spondylarthropathies develops in HLA-B27-transgenic rats. This disease in rats is mediated by CD4+ T cells, but antigen-presenting cells (APCs) may also play a role.
C. Hacquard-Bouder +6 more
semanticscholar +1 more source
OBJECTIVE A disease resembling the human spondylarthropathies develops in HLA-B27-transgenic rats. This disease in rats is mediated by CD4+ T cells, but antigen-presenting cells (APCs) may also play a role.
C. Hacquard-Bouder +6 more
semanticscholar +1 more source
Structure and Immune Recognition of HLA-B27 Antigens: Implications for Disease Association
Scandinavian Journal of Rheumatology, 1990HLA-B27 is strongly associated with susceptibility to ankylosing spondylitis and other spondyloarthropathies. Structural analysis of this antigen has revealed the existence of multiple variants, or subtypes, in human populations. The structural microheterogeneity of these subtypes deeply affects allospecific T cell recognition and most of it occurs at ...
J A López de Castro +4 more
openaire +3 more sources
[Identification of HLA B27 antigen by flow cytometry].
Annales de biologie clinique, 1989Cytofluorograph analysis after immunofluorescence with monoclonal antibodies can be useful for various antigens identification on the surface of cell membrane. This technic is described for antigen HLA B27 identification. This HLA antigen is known indeed to be linked to rhumatismal diseases.
D, Fizet +3 more
openaire +1 more source
CTL Recognize Certain Bacterial Antigens in Association with HLA-B27
1989Cytotoxic T lymphocytes (CTL) can be raised by stimulating in vitro the peripheral blood mononuclear cells (PBMC) of HLA-B27-positive normal individuals (B27+AS−) with autologous cells “modified” by cross-reactive bacterial antigens or modifying factor. These CTL specifically lyse PBMC from HLAB27-positive patients with ankylosing spondylitis (B27+AS+)
Andrew F. Geczy +3 more
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Some features of rheumatoid arthritis in patients with HLA-B27 antigen
Clinical and experimental rheumatology, 1987Some features of rheumatoid arthritis in patients with HLA-B27 ...
Jajić, Zrinka, Jajić, Ivo
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HLA-B12 and HLA-B27 Antigens in Keratoplasty
American Journal of Ophthalmology, 1984Jay H. Krachmer +3 more
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Human HLA-B27 Antigen in Transgenic Mice can Function as a Major Histocompatibility Antigen
1990The revolution of recombinant DNA technology and advances in the manipulation of mouse embryo have made possible experiments only dreamt of before - the ability to isolate and sequence genes, engineer them in specific ways, modulate their expression and even introduce the foreign DNA sequences into the germ line of mice.
Laurent Degos +7 more
openaire +2 more sources