Results 281 to 290 of about 12,878,485 (338)
Some of the next articles are maybe not open access.
Immunology Today, 1996
Abstract The HLA-G antigen is a nonclassical class I major histocompatibility complex molecule. It has a tissue-specific expression on placental extravillous cytotrophoblast cells and, as discussed here, may play an important role in materno-fetal and tissue tolerance.
E D, Carosella +2 more
openaire +2 more sources
Abstract The HLA-G antigen is a nonclassical class I major histocompatibility complex molecule. It has a tissue-specific expression on placental extravillous cytotrophoblast cells and, as discussed here, may play an important role in materno-fetal and tissue tolerance.
E D, Carosella +2 more
openaire +2 more sources
Current Pharmaceutical Design, 2009
Human leukocyte antigen-G (HLA-G) is a non-classical HLA class I molecule, which was first discovered in 1987 by Geraghty and colleagues. While classical HLA class I molecules are expressed on all nucleated cells, the expression of the HLA-G molecule is highly tissue-restricted, such as to placental trophoblast cells.
Jun, Kamishikiryo, Katsumi, Maenaka
openaire +2 more sources
Human leukocyte antigen-G (HLA-G) is a non-classical HLA class I molecule, which was first discovered in 1987 by Geraghty and colleagues. While classical HLA class I molecules are expressed on all nucleated cells, the expression of the HLA-G molecule is highly tissue-restricted, such as to placental trophoblast cells.
Jun, Kamishikiryo, Katsumi, Maenaka
openaire +2 more sources
International Reviews of Immunology, 2021
Human leukocyte antigen G (HLA-G) is a non-classical HLA class I molecule involved in inducing tolerance at the feto-maternal interface and in escape of immune response by tumor cells. The aim of the study is to review the published literature on the expression of HLA-G in malignant melanomas and its clinicopathological and prognostic correlates.A ...
Marletta, Stefano +7 more
openaire +3 more sources
Human leukocyte antigen G (HLA-G) is a non-classical HLA class I molecule involved in inducing tolerance at the feto-maternal interface and in escape of immune response by tumor cells. The aim of the study is to review the published literature on the expression of HLA-G in malignant melanomas and its clinicopathological and prognostic correlates.A ...
Marletta, Stefano +7 more
openaire +3 more sources
Journal of Reproductive Immunology, 1999
We have generated a number of transgenic mice using DNA segments derived from the HLA-G gene. Using these mice we have examined the pattern of expression dictated by HLA-G promoter elements in mice and shown that HLA-G functions both as a restriction element and a transplantation antigen recognized by murine T cells.
A, Mellor, M, Zhou, S J, Conway, D, Munn
openaire +2 more sources
We have generated a number of transgenic mice using DNA segments derived from the HLA-G gene. Using these mice we have examined the pattern of expression dictated by HLA-G promoter elements in mice and shown that HLA-G functions both as a restriction element and a transplantation antigen recognized by murine T cells.
A, Mellor, M, Zhou, S J, Conway, D, Munn
openaire +2 more sources
Reviews of Reproduction, 1997
Recent studies of the nonclassical HLA-G class I gene provide insight into its function(s) during pregnancy. The HLA-G gene can be transcribed in different isoforms resulting from alternative splicings and encoding membrane-bound and soluble proteins.
P, Le Bouteiller, V, Mallet
openaire +3 more sources
Recent studies of the nonclassical HLA-G class I gene provide insight into its function(s) during pregnancy. The HLA-G gene can be transcribed in different isoforms resulting from alternative splicings and encoding membrane-bound and soluble proteins.
P, Le Bouteiller, V, Mallet
openaire +3 more sources
Association of soluble HLA‐G plasma levels with HLA‐G alleles
Tissue Antigens, 2001Abstract:Soluble HLA‐G (sHLA‐G) molecules are found in the peripheral blood of healthy females and males, in cord blood and in amniotic fluids and discussed to be a mediator in maternal‐fetal tolerance. In this study we investigated whether there are allele‐specific differences in expression of sHLA‐G molecules.
V, Rebmann +5 more
openaire +2 more sources
Transcriptional regulation of HLA-G
Transplantation Proceedings, 1999THE EXPRESSION of HLA class I molecules is essential in the immune response, as they present antigenderived peptides to cytotoxic T lymphocytes. The classical HLA class I genes (HLA-A, HLA-B, and HLA-C) are highly polymorphic and are ubiquitously expressed on most somatic cells.
S J, Gobin +4 more
openaire +2 more sources
HLA-G and lymphoproliferative disorders
Seminars in Cancer Biology, 2003The immunomodulatory properties of the HLA-G molecule explain its relevance in malignancies. Our investigations in lymphoproliferative disorders show (i) a frequent and variable distribution of alternatively spliced HLA-G mRNA isoforms, (ii) a rare cell surface expression in diffuse large cell lymphomas with HLA class I loss in half of cases, and (iii)
Laurence, Amiot +9 more
openaire +2 more sources
American Journal of Reproductive Immunology, 2001
PROBLEM: It has been proposed that the expression of the non‐classical MHC class I antigen, HLA‐G, by trophoblast is one mechanism by which the placenta evades attack by maternal uterine NK cells. A similar mechanism is thought to be operative in the escape from immunosurveillance by tumor cells.
B, Davies +4 more
openaire +2 more sources
PROBLEM: It has been proposed that the expression of the non‐classical MHC class I antigen, HLA‐G, by trophoblast is one mechanism by which the placenta evades attack by maternal uterine NK cells. A similar mechanism is thought to be operative in the escape from immunosurveillance by tumor cells.
B, Davies +4 more
openaire +2 more sources